HOXC-AS1: A Promising Drug Target / Biomarker (G100874363)

Target Name: HOXC-AS1

NCBI ID: G100874363

HOXC-AS1

Other Name(s): HOXC cluster antisense RNA 1

HOXC-AS1: A Promising Drug Target / Biomarker

Hoxc-AS1, also known as Hoxc-As1, is a protein that is expressed in the brain and other tissues. It is a key regulator of cell proliferation and has been implicated in a number of neurological and psychiatric disorders. Despite its importance, little is known about this protein, making it a promising target for drug development.

The Hoxc-AS1 gene

The Hoxc-AS1 gene is located on chromosome 6 and encodes a protein that is composed of 254 amino acids. The protein has a molecular weight of 31.9 kDa and a pre-cleaved pleiotropic domain that is involved in its unique structure and function.

The pre-cleaved domain

The pre-cleaved domain of Hoxc-AS1 is a critical region that is involved in the regulation of cell proliferation. It is composed of a single amino acid residue, which is a key structural element in the protein. Studies have shown that the pre-cleaved domain plays a critical role in the formation of a protein-protein interaction network that is involved in the regulation of cell growth and differentiation.

The Hoxc-AS1 protein

Hoxc-AS1 is a protein that is expressed in a variety of tissues, including the brain, heart, and gastrointestinal tract. It is primarily localized to the cytoplasm and is involved in the regulation of cell proliferation, differentiation, and survival.

One of the most significant functions of Hoxc-AS1 is its role in the regulation of cell proliferation. It is a negative regulator of the G1/S transition, which is the process by which cells prepare for cell division. Studies have shown that Hoxc-AS1 plays a critical role in the regulation of G1/S transition by inhibiting the activity of the transcription factor, p21.

In addition to its role in cell proliferation, Hoxc-AS1 is also involved in the regulation of cell differentiation. It is a positive regulator of the Dlx gene, which is involved in the regulation of stem cell differentiation. Studies have shown that Hoxc-AS1 plays a critical role in the regulation of Dlx stem cell differentiation by promoting the activity of the transcription factor, Brn2.

The role of Hoxc-AS1 in neurological and psychiatric disorders

Despite its importance in the regulation of cell proliferation and differentiation, Hoxc-AS1 is also implicated in a number of neurological and psychiatric disorders. One of the most significant findings is the evidence of its involvement in the development and progression of cancer. Studies have shown that Hoxc-AS1 is often overexpressed in a variety of cancer types, including neurobladder cancer, breast cancer, and colorectal cancer.

In addition to its involvement in cancer, Hoxc-AS1 is also implicated in a number of psychiatric and neurological disorders. For example, it is involved in the regulation of the development and progression of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Studies have shown that Hoxc-AS1 is often overexpressed in the brains of individuals with these disorders and that its overexpression may contribute to the development and progression of these disorders.

The potential therapeutic benefits of Hoxc-AS1

The potential therapeutic benefits of Hoxc-AS1 are significant. Given its involvement in the regulation of cell proliferation and differentiation, as well as its involvement in the regulation of cancer and neurodegenerative disorders, Hoxc-AS1 may be a promising target for drug development.

One potential approach to targeting Hoxc-AS1 is the use of small molecules that can inhibit its activity.

Protein Name: HOXC Cluster Antisense RNA 1

The "HOXC-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HOXC-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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