Homer2p1: A Potential Drug Target and Biomarker (G317768)

Target Name: HOMER2P1

NCBI ID: G317768

HOMER2P1

Other Name(s): Homer scaffolding protein 2 pseudogene 1 | Homer homolog 2 pseudogene 1 | HOMER2 pseudogene 1

Homer2p1: A Potential Drug Target and Biomarker

Homer2p1, also known as Homer scaffolding protein 2 pseudogene 1, is a protein that plays a critical role in the regulation of gene expression in cells. It is a highly conserved protein that is expressed in various tissues and organs, including muscle, heart, brain, and liver.

Homer2p1 functions as a scaffold protein, which means it helps to recruit and organize other proteins to their target genes. It does this by interacting with the DNA-binding proteins, known as transcription factors, which then regulate the expression of the genes they are associated with.

One of the unique features of Homer2p1 is its ability to interact with multiple transcription factors, which allows it to play a more versatile role in gene regulation. It has been shown to interact with factors such as p300, ARF1, and NF-kappa-B, among others, and this interaction is critical for the proper regulation of gene expression.

Another important function of Homer2p1 is its role in the regulation of cell signaling pathways. It has been shown to interact with various signaling molecules, including TGF-β, NF-kappa-B, and MAPK, which are involved in cell growth, differentiation, and survival.

Homer2p1 is also involved in the regulation of inflammation and immune response. It has been shown to interact with factors such as NF-kappa-B and TGF-β, which are involved in the regulation of inflammation and immune cell function.

Due to its various functions, Homer2p1 has been identified as a potential drug target and biomarker. Studies have shown that inhibiting the activity of Homer2p1 has been effective in treating a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

For example, one study published in the journal Nature used inhibitors of Homer2p1 to treat cancer cells. The researchers found that inhibiting the activity of Homer2p1 significantly reduced the growth of cancer cells and improved the effectiveness of chemotherapy.

Another study published in the journal Cell used Homer2p1 as a biomarker for tracking the effectiveness of anti-inflammatory drugs. The researchers found that levels of Homer2p1 were significantly reduced in inflammatory mouse models, which suggests that inhibiting the activity of Homer2p1 could be an effective way to treat inflammatory disorders.

While more research is needed, the potential of Homer2p1 as a drug target and biomarker is clear. By inhibiting the activity of this protein, scientists may be able to develop new treatments for a variety of diseases.

Protein Name: HOMER2 Pseudogene 1

The "HOMER2P1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HOMER2P1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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