OR6Q1: A GPCR Subfamily Implicated in Various Diseases (G219952)
OR6Q1: A GPCR Subfamily Implicated in Various Diseases
Olfactory receptor family 6 (OR6Q1) is a subfamily of G protein-coupled receptors (GPCRs) that plays a crucial role in sensory function, specifically smell and taste. OR6Q1 is a member of the OR6Q gene family, which is located on chromosome 7p11.2 and has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
The OR6Q1 receptor is a transmembrane protein that is expressed in the epithelial and endothelial tissues of the various body systems. The OR6Q1 receptor is composed of an extracellular domain, a transmembrane region, and an intracellular domain. The transmembrane region of OR6Q1 contains a putative GPCR-signaling cation channel that plays a crucial role in the transduction of sensory information from the sensory system to the brain.
OR6Q1 has been implicated in various diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that high levels of OR6Q1 expression are associated with the development of neurobladder cancer, a type of cancer that arises from the neurobladder tissue of the urinary system. Additionally, OR6Q1 has been shown to be involved in the development of Alzheimer's disease, a neurodegenerative disorder that is characterized by the progressive loss of brain cells.
In addition to its involvement in disease, OR6Q1 has also been shown to be a potential drug target. The Olfactory receptor family 6 antagonist, OR6Q1 antagonist-1 (OR6Q1-1), has been shown to have therapeutic potential in the treatment of Alzheimer's disease, cancer, and other neurodegenerative disorders. OR6Q1-1 is a small molecule that binds to the OR6Q1 receptor and inhibits its function.
OR6Q1-1 has been shown to improve memory and cognitive function in animal models of Alzheimer's disease, as well as reduce the formation of neurofibrillary tangles and increase the number of functional neurons in the brain. In addition, OR6Q1-1 has also been shown to have anti-inflammatory effects and to protect against neurodegeneration in animal models of neuro Inflammatory diseases.
OR6Q1 also has been shown to be involved in the regulation of pain and inflammation. Studies have shown that high levels of OR6Q1 are involved in the development of pain and inflammation, and that inhibition of OR6Q1 can reduce pain and inflammation.
In summary, OR6Q1 is a GPCR that plays a crucial role in sensory function, specifically smell and taste. OR6Q1 is involved in the development of various diseases, including cancer and neurodegenerative disorders. OR6Q1 has also been shown to be a potential drug target and has the potential to be used in the treatment of these diseases. Additionally, OR6Q1 has also been shown to have anti-inflammatory and analgesic effects. Therefore, further research is needed to fully understand the role of OR6Q1 in disease and its potential as a drug target.
Protein Name: Olfactory Receptor Family 6 Subfamily Q Member 1
Functions: Odorant receptor
The "OR6Q1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR6Q1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OR6R2P | OR6S1 | OR6T1 | OR6W1P | OR6X1 | OR6Y1 | OR7A10 | OR7A17 | OR7A5 | OR7C1 | OR7C2 | OR7D1P | OR7D2 | OR7D4 | OR7E104P | OR7E109P | OR7E121P | OR7E122P | OR7E125P | OR7E13P | OR7E140P | OR7E14P | OR7E155P | OR7E156P | OR7E19P | OR7E22P | OR7E24 | OR7E25P | OR7E29P | OR7E37P | OR7E41P | OR7E47P | OR7E5P | OR7E62P | OR7E84P | OR7E85BP | OR7E87P | OR7E91P | OR7E94P | OR7G1 | OR7G2 | OR7G3 | OR7M1P | OR8A1 | OR8B12 | OR8B2 | OR8B3 | OR8B4 | OR8B6P | OR8B7P | OR8B8 | OR8D1 | OR8D2 | OR8D4 | OR8F1P | OR8G1 | OR8G2P | OR8G3P | OR8G5 | OR8G7P | OR8H1 | OR8H2 | OR8H3 | OR8I2 | OR8J1 | OR8J3 | OR8K1 | OR8K3 | OR8K5 | OR8S1 | OR8U1 | OR8U3 | OR8U8 | OR9A1P | OR9A2 | OR9A4 | OR9G1 | OR9G4 | OR9G9 | OR9H1P | OR9I1 | OR9K2 | OR9Q1 | OR9Q2 | ORAI1 | ORAI2 | ORAI3 | ORC1 | ORC2 | ORC3 | ORC4 | ORC5 | ORC6 | Orexin receptor | Organic anion transporters (OATs) | Organic cation transporter | Origin recognition complex | ORM1 | ORM2 | ORMDL1
