OR6R2P: A Potential Drug Target and Biomarker for ORR6R2P Function and Dysfunction
OR6R2P: A Potential Drug Target and Biomarker for ORR6R2P Function and Dysfunction
Olfactory receptor family 6 (OR6R2P) is a subfamily of the olfactory receptor family that plays a crucial role in human sensory function. OR6R2P is composed of two genes, OR6R2P1 and OR6R2P2, which encode for the protein OR6R2P. OR6R2P is expressed in the sensory neurons of the brain and is involved in the detection of various sensory stimuli, including smell, taste, and touch.
Diseases associated with OR6R2P dysfunction
OR6R2P dysfunction has been implicated in various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and chronic insomnia. In these conditions, individuals have reduced or lost their ability to detect and respond to different sensory stimuli. This is thought to be due to dysfunction in the OR6R2P protein, which is involved in the detection and processing of sensory information.
OR6R2P as a drug target
OR6R2P has been identified as a potential drug target for several reasons. Firstly, OR6R2P is involved in the modulation of pain perception, which makes it an attractive target for pain therapies. Secondly, OR6R2P is involved in the regulation of anxiety and depression, which makes it an attractive target for anxiety and depression treatments. Thirdly, OR6R2P is involved in the regulation of sleep-wake cycle, which makes it an attractive target for insomnia treatments.
OR6R2P as a biomarker
OR6R2P has also been identified as a potential biomarker for several diseases, including Alzheimer's disease and Parkinson's disease. This is because the dysfunction in OR6R2P is often associated with the accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, which are hallmark lesions of these conditions. Additionally, individuals with Parkinson's disease have lower levels of OR6R2P than healthy individuals, which suggests that OR6R2P may be a useful biomarker for this condition.
OR6R2P function and regulation
OR6R2P is a transmembrane protein that is involved in the regulation of various sensory functions, including smell and taste. It is composed of two distinct chains, each of which contains a unique protein domain. The N-terminus of OR6R2P contains a putative transmembrane domain that is involved in the formation of a complex with other proteins. The C-terminus of OR6R2P contains a protein domain that is involved in the regulation of sensory perception, including the modulation of pain perception and the regulation of anxiety and depression.
OR6R2P is regulated by several intracellular signaling pathways, including the TGF-β pathway and the neurotrophin pathway. These signaling pathways are involved in the regulation of OR6R2P function, including the modulation of sensory perception and the regulation of pain perception, anxiety, and depression.
OR6R2P as a drug target
OR6R2P has been identified as a potential drug target for several reasons. Firstly, OR6R2P is involved in the modulation of pain perception, which makes it an attractive target for pain therapies. Secondly, OR6R2P is involved in the regulation of anxiety and depression, which makes it an attractive target for anxiety and depression treatments. Thirdly, OR6R2P is involved in the regulation of sleep-wake cycle, which makes it an attractive target for insomnia treatments.
OR6R2P has been targeted by several drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs), which have been shown to inhibit OR6R2P function. Additionally, OR6R2P has also been targeted by several small molecules and peptides that have been shown to modulate OR6R2P function.
OR6R2P as a biomarker
OR6R2P has also been identified as a potential biomarker for several diseases, including Alzheimer's disease and Parkinson's disease. This is because the dysfunction in OR6R2P is often associated with the accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, which are hallmark lesions of these conditions. Additionally, individuals with Parkinson's disease have lower levels of OR6R2P than healthy individuals, which suggests that OR6R2P may be a useful biomarker for this condition.
OR6R2P function and regulation
OR6R2P is a transmembrane protein that is involved in
Protein Name: Olfactory Receptor Family 6 Subfamily R Member 2 Pseudogene
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More Common Targets
OR6S1 | OR6T1 | OR6W1P | OR6X1 | OR6Y1 | OR7A10 | OR7A17 | OR7A5 | OR7C1 | OR7C2 | OR7D1P | OR7D2 | OR7D4 | OR7E104P | OR7E109P | OR7E121P | OR7E122P | OR7E125P | OR7E13P | OR7E140P | OR7E14P | OR7E155P | OR7E156P | OR7E19P | OR7E22P | OR7E24 | OR7E25P | OR7E29P | OR7E37P | OR7E41P | OR7E47P | OR7E5P | OR7E62P | OR7E84P | OR7E85BP | OR7E87P | OR7E91P | OR7E94P | OR7G1 | OR7G2 | OR7G3 | OR7M1P | OR8A1 | OR8B12 | OR8B2 | OR8B3 | OR8B4 | OR8B6P | OR8B7P | OR8B8 | OR8D1 | OR8D2 | OR8D4 | OR8F1P | OR8G1 | OR8G2P | OR8G3P | OR8G5 | OR8G7P | OR8H1 | OR8H2 | OR8H3 | OR8I2 | OR8J1 | OR8J3 | OR8K1 | OR8K3 | OR8K5 | OR8S1 | OR8U1 | OR8U3 | OR8U8 | OR9A1P | OR9A2 | OR9A4 | OR9G1 | OR9G4 | OR9G9 | OR9H1P | OR9I1 | OR9K2 | OR9Q1 | OR9Q2 | ORAI1 | ORAI2 | ORAI3 | ORC1 | ORC2 | ORC3 | ORC4 | ORC5 | ORC6 | Orexin receptor | Organic anion transporters (OATs) | Organic cation transporter | Origin recognition complex | ORM1 | ORM2 | ORMDL1 | ORMDL2
