RAB43: Key Regulator of Cell Signaling and Survival (G339122)

Target Name: RAB43

NCBI ID: G339122

RAB43

RAB43: Key Regulator of Cell Signaling and Survival

RAB43 is a protein that is expressed in many tissues throughout the body. It is a member of the Rab gene family, which is known for the production of small GTPases. These proteins play a crucial role in regulating various cellular processes, including cell signaling, intracellular signaling, and cell survival. RAB43 is a key regulator of the RAB43/MAPK signaling pathway, which is involved in a wide range of cellular processes, including cell growth, differentiation, and survival.

The RAB43 protein is composed of 211 amino acid residues and has a calculated molecular mass of 21.1 kDa. It is expressed in many tissues throughout the body, including the brain, heart, skeletal muscles, and reproductive organs. It is highly expressed in the brain, where it is a key regulator of synaptic plasticity, learning, and memory.

RAB43 functions as a negative regulator of the RAB43/MAPK signaling pathway. This pathway is involved in a wide range of cellular processes, including cell signaling, intracellular signaling, and cell survival. The RAB43 protein is a key regulator of the RAB43/MAPK signaling pathway, as it promotes the inhibition of the activity of the MAPK/ERK signaling pathway.

The RAB43/MAPK signaling pathway is a critical pathway involved in many cellular processes. It is involved in the regulation of cell growth, differentiation, and survival, as well as the regulation of cell signaling and intracellular signaling. The RAB43 protein plays a crucial role in this pathway by promoting the inhibition of the activity of the MAPK/ERK signaling pathway.

The RAB43 protein is also involved in the regulation of many cellular processes, including cell adhesion, migration, and invasion. It is a key regulator of the cadherin/FAK signaling pathway, which is involved in the regulation of cell adhesion and migration. The RAB43 protein is also involved in the regulation of the Src/FAK signaling pathway, which is involved in the regulation of cell signaling and invasion.

In addition to its role in the RAB43/MAPK and cadherin/FAK signaling pathways, the RAB43 protein is also involved in the regulation of many other cellular processes. It is a key regulator of the PI3K/AKT signaling pathway, which is involved in the regulation of cell signaling and metabolism. The RAB43 protein is also involved in the regulation of the TOR signaling pathway, which is involved in the regulation of cell signaling and metabolism.

The RAB43 protein is a potential drug target and biomarker for a wide range of diseases. Its involvement in the regulation of the RAB43/MAPK and PI3K/AKT signaling pathways makes it a potential target for small molecule inhibitors. The RAB43 protein is also involved in the regulation of many cellular processes, including cell adhesion, migration, and invasion, which makes it a potential target for biomarkers that are used to monitor disease progression.

In conclusion, RAB43 is a protein that is involved in the regulation of many cellular processes throughout the body. It is a key regulator of the RAB43/MAPK signaling pathway and is involved in the regulation of cell growth, differentiation, and survival. The RAB43 protein is a potential drug target and biomarker for a wide range of diseases, due to its involvement in the regulation of various cellular processes. Further research is needed to fully understand the role of RAB43 in cellular processes and its potential as a drug target and biomarker.

Protein Name: RAB43, Member RAS Oncogene Family

Functions: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis

The "RAB43 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RAB43 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets