Target Name: C1GALT1
NCBI ID: G56913
Review Report on C1GALT1 Target / Biomarker Content of Review Report on C1GALT1 Target / Biomarker
C1GALT1
Other Name(s): core 1 beta3-Gal-T1 | C1GALT | Core 1 beta1,3-galactosyltransferase 1 | Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 | epididymis secretory sperm binding protein | C1GalT1 | core 1 O-glycan T-synthase | Beta-1,3-galactosyltransferase | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | Core 1 O-glycan T-synthase | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | T-synthase | C1GLT_HUMAN | OTTHUMP00000200760 | B3Gal-T8 | Core 1 beta3-Gal-T1 | core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 | Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Understanding The Function of C1GALT1

C1GALT1, also known as core 1 beta3-Gal-T1, is a protein that is expressed in various tissues throughout the body. It is a member of the Gal-T family of proteins, which are involved in the intracellular signaling pathway known as the Galt-7 signaling pathway. This pathway is involved in a wide range of physiological processes, including cell growth, differentiation, and survival.

One of the unique features of C1GALT1 is its ability to interact with the protein known as ALYLAMIN (ALYL) on the surface of various cell types. This interaction allows C1GALT1 to influence the activity of ALYL, which in turn can affect the expression of genes involved in cell growth, differentiation, and survival.

C1GALT1 is also known for its role in the regulation of cell adhesion. This protein is involved in the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain the integrity of tissues.

In addition to its role in cell signaling and adhesion, C1GALT1 is also involved in the regulation of inflammation. This protein has been shown to play a key role in the regulation of immune responses and the production of inflammatory cytokines.

Despite its many functions, C1GALT1 is not yet a well-established drug target or biomarker. This is because while there is some evidence to suggest that this protein may be involved in a wide range of biological processes, more research is needed to fully understand its role in these processes.

One potential way to study the role of C1GALT1 could be to use techniques such as RNA interference or gene editing to knockdown or activate the expression of this protein. This would allow researchers to study its effects on various cellular processes and gain a better understanding of its role in these processes.

Another potential way to study the role of C1GALT1 could be to use antibodies or other proteins to study its interactions with other proteins. This would allow researchers to determine the specific mechanisms by which C1GALT1 influences the activity of these proteins and further understand its role in various biological processes.

Overall, while C1GALT1 is an interesting protein with a wide range of potential functions, more research is needed to fully understand its role in various biological processes. As such, it remains a promising target for future research and the development of new drugs.

Protein Name: Core 1 Synthase, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

Functions: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development

The "C1GALT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C1GALT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

C1GALT1C1 | C1GALT1C1L | C1orf100 | C1orf105 | C1orf109 | C1orf112 | C1orf115 | C1orf116 | C1orf122 | C1orf127 | C1orf131 | C1orf141 | C1orf146 | C1orf159 | C1orf162 | C1orf167 | C1orf185 | C1orf198 | C1orf21 | C1orf210 | C1orf216 | C1orf220 | C1orf226 | C1orf35 | C1orf43 | C1orf50 | C1orf52 | C1orf53 | C1orf54 | C1orf56 | C1orf68 | C1orf74 | C1orf87 | C1orf94 | C1QA | C1QB | C1QBP | C1QC | C1QL1 | C1QL2 | C1QL3 | C1QL4 | C1QTNF1 | C1QTNF1-AS1 | C1QTNF12 | C1QTNF2 | C1QTNF3 | C1QTNF3-AMACR | C1QTNF4 | C1QTNF5 | C1QTNF6 | C1QTNF7 | C1QTNF7-AS1 | C1QTNF8 | C1QTNF9 | C1QTNF9B | C1R | C1RL | C1RL-AS1 | C1S | C2 | C2-AS1 | C20orf141 | C20orf144 | C20orf173 | C20orf181 | C20orf202 | C20orf203 | C20orf204 | C20orf27 | C20orf85 | C20orf96 | C21orf58 | C21orf62 | C21orf62-AS1 | C21orf91 | C21orf91-OT1 | C22orf15 | C22orf23 | C22orf31 | C22orf39 | C22orf42 | C22orf46P | C2CD2 | C2CD2L | C2CD3 | C2CD4A | C2CD4B | C2CD4C | C2CD4D | C2CD4D-AS1 | C2CD5 | C2CD6 | C2orf15 | C2orf16 | C2orf27A | C2orf42 | C2orf48 | C2orf49 | C2orf50