Target Name: C1orf146
NCBI ID: G388649
Review Report on C1orf146 Target / Biomarker Content of Review Report on C1orf146 Target / Biomarker
C1orf146
Other Name(s): RP11-163M2.4 | synaptonemal complex reinforcing element | SPO16 | uncharacterized protein C1orf146 | SPO16_HUMAN | Chromosome 1 open reading frame 146 | Uncharacterized protein C1orf146 | Protein SPO16 homolog | chromosome 1 open reading frame 146 | SCRE | Synaptonemal complex reinforcing element

Unlocking the Potential of C1orf146 (RP11-163M2.4) as a Drug Target and Biomarker

C1orf146 (RP11-163M2.4) is a highly conserved non-coding RNA molecule that has been annotated as a potential regulator of gene expression in various organisms, including humans. Its unique feature is its ability to interact with protein-coding genes, leading to the formation of RNA-protein complex, which can modulate gene expression and contribute to the regulation of cellular processes.

RP11-163M2.4, as a RNA-protein complex regulator, has been implicated in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. Its role in these processes makes it an attractive drug target and a potential biomarker for various diseases.

Drug Target Potential

RP11-163M2.4 has been identified as a potential drug target due to its involvement in cell growth, apoptosis, and transcriptional regulation. various studies have demonstrated that inhibiting RP11-163M2.4 can lead to the inhibition of cell growth, apoptosis, and various cellular processes that are associated with cancer progression.

One of the key mechanisms by which RP11-163M2.4 regulates cell growth is its role in the regulation of the cell cycle. RP11-163M2.4 has been shown to interact with the protein tyrosine kinase (PTK), which is a key regulator of the cell cycle. This interaction between RP11-163M2.4 and PTK suggests that RP11-163M2.4 may play a role in the regulation of cell cycle progression and the maintenance of cellular homeostasis.

In addition to its role in cell cycle regulation, RP11-163M2.4 has also been shown to contribute to the regulation of apoptosis. The loss of cellular homeostasis and the regulation of apoptosis are crucial for the survival of living organisms. RP11-163M2.4 has been shown to play a role in the regulation of apoptosis by interacting with the protein Bcl-2. Bcl-2 is a key regulator of apoptosis and has been implicated in various diseases, including cancer.

Biomarker Potential

RP11-163M2.4 has also been identified as a potential biomarker for various diseases due to its unique ability to interact with protein-coding genes. The regulation of gene expression by RP11-163M2.4 has been shown to contribute to the regulation of cellular processes that are associated with disease development.

One of the key applications of RP11-163M2.4 as a biomarker is its potential to serve as a therapeutic target for cancer. The regulation of gene expression by RP11-163M2.4 has been shown to contribute to the regulation of various cellular processes that are associated with cancer progression. By targeting RP11-163M2.4, researchers may be able to develop new treatments for cancer.

Conclusion

RP11-163M2.4 is a highly conserved non-coding RNA molecule that has been implicated in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. Its unique ability to interact with protein-coding genes makes it an attractive drug target and a potential biomarker for various diseases. Further research is needed to fully understand the role of RP11-163M2.4 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Chromosome 1 Open Reading Frame 146

Functions: Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells (By similarity). Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 (By similarity). Required for the localization of TEX11 and MSH4 to recombination intermediates (By similarity)

The "C1orf146 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about C1orf146 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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