Target Name: MIR148A
NCBI ID: G406940
Review Report on MIR148A Target / Biomarker Content of Review Report on MIR148A Target / Biomarker
MIR148A
Other Name(s): hsa-miR-148a-3p | hsa-mir-148a | mir-148a | MIRN148 | microRNA 148a | MicroRNA 148a | hsa-mir-148 | Hsa-mir-148 | MIRN148A | hsa-miR-148a-5p

MIR148A: A Drug Target and Biomarker for Chronic Pain

Introduction

Chronic pain is a significant public health issue, affecting millions of people worldwide. The constant and severe pain can have a significant impact on an individual's quality of life, and it can even lead to depression and anxiety. The identification of potential drug targets and biomarkers for chronic pain has the potential to improve treatment outcomes and alleviate suffering. In this article, we will explore MIR148A, a potential drug target and biomarker for chronic pain.

MIR148A: The Potential Drug Target

MIR148A is a microRNA (miRNA), a small non-coding RNA molecule that plays a critical role in gene expression. MIR148A has been identified as a potential drug target for chronic pain due to its involvement in the regulation of pain signaling pathways.

The pain signaling pathway is a complex cascade that involves the perception of pain by the central nervous system (CNS) and the production of pain-related cytokines by peripheral tissues. MIR148A has been shown to regulate the activity of several pain-related genes, including TrkA, TrkB, and TrkC, which encode for components of the pain signaling pathway.

In addition to its role in pain signaling, MIR148A has also been shown to play a role in the regulation of inflammation and immune response. MIR148A has been shown to downregulate the activity of several pro-inflammatory genes, including COX-2, which may help to reduce inflammation and improve pain outcomes.

MIR148A: The Potential Biomarker

MIR148A has also been identified as a potential biomarker for chronic pain due to its expression level. Studies have shown that MIR148A has been shown to be downregulated in chronic pain populations, which may indicate that it could serve as a potential biomarker for pain.

In addition to its potential as a drug target and biomarker, MIR148A is also of interest due to its potential role in the regulation of stem cell proliferation. MIR148A has been shown to promote the proliferation of progenitor cells, which may have implications for the development of new treatments for chronic pain.

Conclusion

MIR148A is a potential drug target and biomarker for chronic pain due to its involvement in the regulation of pain signaling pathways and its potential role in the regulation of stem cell proliferation. Further research is needed to fully understand the potential of MIR148A as a drug target and biomarker for chronic pain.

Protein Name: MicroRNA 148a

The "MIR148A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR148A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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