Target Name: MPP2
NCBI ID: G4355
Review Report on MPP2 Target / Biomarker Content of Review Report on MPP2 Target / Biomarker
MPP2
Other Name(s): Discs large homolog 2 | MMP2 | Protein MPP2 | discs large homolog 2 | MAGUK p55 scaffold protein 2 | discs large, homolog 2 | MPP2 variant 1 | MAGUK p55 subfamily member 2 (isoform 1) | MAGUK p55 subfamily member 2 | MAGUK p55 scaffold protein 2, transcript variant 1 | DLG2 | MPP2_HUMAN | membrane palmitoylated protein 2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)

MPP2: Mitochondrial Protein Regulator

MPP2, orDiscs large homolog 2, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of theMPP2 gene family, which encodes a family of proteins that are involved in the regulation of mitochondrial dynamics and energy metabolism.

One of the unique features of MPP2 is its ability to interact with other proteins that are involved in the same process. This interaction allows MPP2 to play a role in a wide range of biological processes, including the regulation of muscle contractions, the movement of proteins into the mitochondria, and the metabolism of fats and carbohydrates.

One of the ways that MPP2 is involved in these processes is through its ability to interact with the protein known as CoA-SH, which is involved in the citric acid cycle. This interaction allows MPP2 to regulate the levels of CoA-SH in the mitochondria, which in turn affects the levels of energy available for cellular processes.

Another way that MPP2 is involved in these processes is through its ability to interact with the protein known as FAT/ADP ratio. This interaction allows MPP2 to regulate the levels of fat and carbohydrate in the body, which is important for maintaining energy homeostasis.

MPP2 is also involved in the regulation of cellular signaling pathways that are important for many different processes in the body. For example, it is involved in the regulation of the signaling pathway that is responsible for the development and maintenance of muscle mass, and it is also involved in the regulation of the signaling pathway that is responsible for the regulation of inflammation.

In addition to its role in cellular signaling pathways, MPP2 is also involved in the regulation of mitochondrial dynamics and energy metabolism. This includes the regulation of the levels of mitochondrial protein, such as

Protein Name: MAGUK P55 Scaffold Protein 2

Functions: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017)

The "MPP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MPP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MPP3 | MPP4 | MPP7 | MPPE1 | MPPED1 | MPPED2 | MPPED2-AS1 | MPRIP | MPST | MPTX1 | MPV17 | MPV17L | MPV17L2 | MPZ | MPZL1 | MPZL2 | MPZL3 | MR1 | MRAP | MRAP2 | MRAS | MRC1 | MRC2 | MRE11 | MREG | MRFAP1 | MRFAP1L1 | MRGBP | MRGPRD | MRGPRE | MRGPRF | MRGPRF-AS1 | MRGPRG | MRGPRX1 | MRGPRX2 | MRGPRX3 | MRGPRX4 | MRI1 | MRLN | MRM1 | MRM2 | MRM3 | MRNIP | MRO | MROCKI | MROH1 | MROH2A | MROH2B | MROH3P | MROH5 | MROH6 | MROH7 | MROH7-TTC4 | MROH8 | MROH9 | MRPL1 | MRPL10 | MRPL11 | MRPL12 | MRPL13 | MRPL14 | MRPL15 | MRPL16 | MRPL17 | MRPL18 | MRPL19 | MRPL2 | MRPL20 | MRPL20-AS1 | MRPL20P1 | MRPL21 | MRPL22 | MRPL23 | MRPL23-AS1 | MRPL24 | MRPL27 | MRPL28 | MRPL3 | MRPL30 | MRPL33 | MRPL34 | MRPL35 | MRPL35P2 | MRPL37 | MRPL38 | MRPL39 | MRPL4 | MRPL40 | MRPL41 | MRPL42 | MRPL42P5 | MRPL43 | MRPL44 | MRPL45 | MRPL45P1 | MRPL45P2 | MRPL46 | MRPL47 | MRPL48 | MRPL49