Target Name: OR4Q3
NCBI ID: G441669
Review Report on OR4Q3 Target / Biomarker Content of Review Report on OR4Q3 Target / Biomarker
OR4Q3
Other Name(s): olfactory receptor 4Q4 | Olfactory receptor 4Q3 | OR4Q3_HUMAN | olfactory receptor, family 4, subfamily Q, member 4 | c14_5008 | HSA6 | olfactory receptor OR14-3 | OR4Q4 | Olfactory receptor 4Q4 | Olfactory receptor, family 4, subfamily Q, member 4 | OR14-3 | Olfactory receptor OR14-3 | olfactory receptor family 4 subfamily Q member 3 | C14_5008 | C14orf13 | Olfactory receptor family 4 subfamily Q member 3

OR4Q3: Olfactory Receptor 4Q4

OR4Q3, also known as olfactory receptor 4Q4, is a protein that is expressed in the olfactory system of the human nose. It is a member of the G protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling. OR4Q3 is specifically expressed in the lateral olfactory cortical neurons, which are responsible for the perception of odor.

The olfactory system is an essential part of the sense of smell, and the ability to detect and interpret the scents that we sense is critical for our survival. Olfactory neurons are located in the nasal cavity and are responsible for transmitting information about the smells that we sense to the brain. They are made up of a single layer of olfactory epithelial cells, which are connected to the underlying nervous system by the olfactory nerve. When a smell is sensed, the olfactory neurons send a signal to the brain via the olfactory nerve.

OR4Q3 is one of the proteins that is involved in the olfactory system. It is a GPCR that is characterized by a long extracellular flap in its transmembrane domain, which is involved in the formation of the protein-protein interaction that is critical for its function. OR4Q3 is also known for its role in the regulation of the olfactory neuron axon, which is the structure that carries the olfactory nerve from the brain to the nose.

Studies have shown that OR4Q3 is involved in a wide range of physiological processes that are important for the function of the olfactory system. For example, it has been shown to be involved in the regulation of sensory input, the modulation of pain responses, and the regulation of inflammation. It is also thought to play a role in the development and progression of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease.

Due to its involvement in the olfactory system, OR4Q3 has been considered as a potential drug target or biomarker for a variety of diseases. For example, studies have shown that inhibiting the activity of OR4Q3 can protect against neurodegenerative diseases, including Alzheimer's and Parkinson's disease. This is because the activity of OR4Q3 is involved in the regulation of the outflow of blood to the brain, which is thought to be a key factor in the development of these diseases.

In addition, OR4Q3 has also been shown to be involved in the regulation of pain responses. Studies have shown that inhibiting the activity of OR4Q3 can reduce the pain that is perceived by the nervous system. This is thought to be because OR4Q3 is involved in the regulation of the release of endogenous opioids, which are natural painkillers.

Furthermore, OR4Q3 is also involved in the regulation of inflammation. Studies have shown that increasing the activity of OR4Q3 can increase the production of pro-inflammatory cytokines, which are thought to play a key role in the development of inflammatory diseases. In contrast, inhibiting the activity of OR4Q3 can reduce the production of these cytokines and protect against inflammation.

In conclusion, OR4Q3 is a protein that is expressed in the olfactory system of the human nose and is involved in a wide range of physiological processes that are important for the function of the olfactory system. It is a potential drug target or biomarker for a variety of diseases, including neurodegenerative diseases, pain responses, and inflammation. Further research is needed to fully understand the role of OR4Q3 in these processes and to develop effective treatments for these diseases.

Protein Name: Olfactory Receptor Family 4 Subfamily Q Member 3

Functions: Odorant receptor

The "OR4Q3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR4Q3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OR4S1 | OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2 | OR51F1 | OR51F2 | OR51G1 | OR51G2 | OR51H1 | OR51I1 | OR51I2 | OR51J1 | OR51L1 | OR51M1 | OR51Q1 | OR51S1 | OR51T1 | OR51V1 | OR52A1 | OR52A4P | OR52A5 | OR52B2 | OR52B4 | OR52B6 | OR52D1 | OR52E1 | OR52E2 | OR52E4 | OR52E5 | OR52E6 | OR52E8 | OR52H1 | OR52I1 | OR52I2 | OR52J3 | OR52K1 | OR52K2 | OR52K3P | OR52L1 | OR52M1 | OR52N1 | OR52N4 | OR52N5 | OR52R1 | OR52W1 | OR52Z1P | OR56A1 | OR56A3 | OR56A4 | OR56A5 | OR56B1 | OR56B4 | OR5A1 | OR5A2 | OR5AC1 | OR5AC2 | OR5AK2 | OR5AK4P | OR5AN1 | OR5AP2 | OR5AR1 | OR5AS1 | OR5AU1 | OR5B12 | OR5B17 | OR5B2 | OR5B21 | OR5B3 | OR5BA1P | OR5C1 | OR5D13 | OR5D14 | OR5D16 | OR5D17P | OR5D18 | OR5E1P | OR5F1 | OR5H1 | OR5H14 | OR5H15 | OR5H2 | OR5H4P | OR5H6 | OR5I1