Target Name: SORBS2
NCBI ID: G8470
Review Report on SORBS2 Target / Biomarker Content of Review Report on SORBS2 Target / Biomarker
SORBS2
Other Name(s): Sorbin and SH3 domain-containing protein 2 (isoform 9) | arg-binding protein 2 | OTTHUMP00000211726 | Sorbin and SH3 domain-containing protein 2 (isoform 2) | Arg-binding protein 2 | SRBS2_HUMAN | Sorbin and SH3 domain containing 2 | ARGBP2 | sorbin and SH3 domain containing 2 | OTTHUMP00000211728 | ArgBP2 | FLJ93447 | Sorbin and SH3 domain-containing protein 2 | Arg binding protein 2 | Arg/Abl interacting protein | KIAA0777 | Arg/Abl-interacting protein 2 | PRO0618 | Sorbin and SH3 domain containing 2, transcript variant 9 | OTTHUMP00000211723 | SORBS2 variant 9 | Sorbin | SORBS2 variant 2 | Sorbin and SH3 domain containing 2, transcript variant 2

SORBS2: A Potential Drug Target and Biomarker

Sorbin and SH3 domain-containing protein 2 (ISOform 9), also known as SORBS2, is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug or biomarker has led to a growing interest in the study of this protein in recent years.

SORBS2 is a protein that is expressed in a variety of tissues and cells in the body, including the brain, heart, liver, and muscle. It is characterized by the presence of a Sorbin-like domain and a SH3 domain, which give it its unique structure and function. The Sorbin-like domain is a conserved region that is found in a variety of proteins, including the protein SORCS1, which is also known as SMY/YAF-1, and is involved in the regulation of DNA binding and gene expression. The SH3 domain, on the other hand, is a unique region that is found in only a few proteins and is involved in the regulation of protein-protein interactions and the structure of proteins.

SORBS2 is involved in a variety of cellular processes that are important for normal physiological function. For example, it is involved in the regulation of cell adhesion, which is critical for the development and maintenance of tissues and organs. It is also involved in the regulation of cell signaling, which is essential for the proper functioning of tissues and organs. In addition, SORBS2 is involved in the regulation of protein degradation, which is important for maintaining the homeostasis of tissues and organs.

SORBS2 has also been shown to be involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that SORBS2 is involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In addition, SORBS2 has been shown to be involved in the development of certain autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

Due to its unique structure and function, SORBS2 has been identified as a potential drug target and biomarker. Researchers are interested in studying the effects of drugs on SORBS2 and its function in order to develop new treatments for various diseases. In addition, SORBS2's unique structure and function make it an attractive target for researchers to study in order to gain new insights into the regulation of protein-protein interactions and the regulation of cellular processes.

In conclusion, SORBS2 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function make it an attractive target for researchers to investigate, and its potential as a drug or biomarker has led to a growing interest in this protein in recent years. Further research is needed to fully understand the functions of SORBS2 and its potential as a drug target and biomarker.

Protein Name: Sorbin And SH3 Domain Containing 2

Functions: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder

The "SORBS2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SORBS2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SORBS3 | SORCS1 | SORCS2 | SORCS3 | SORCS3-AS1 | SORD | SORD2P | SORL1 | SORT1 | Sorting and assembly machinery complex | Sorting nexin | SOS1 | SOS2 | SOSS complex | SOST | SOSTDC1 | SOWAHA | SOWAHB | SOWAHC | SOWAHD | SOX1 | SOX1-OT | SOX10 | SOX11 | SOX12 | SOX13 | SOX14 | SOX15 | SOX17 | SOX18 | SOX2 | SOX2-OT | SOX21 | SOX21-AS1 | SOX3 | SOX30 | SOX30P1 | SOX4 | SOX5 | SOX5-AS1 | SOX6 | SOX7 | SOX8 | SOX9 | SOX9-AS1 | SP1 | SP100 | SP110 | SP140 | SP140L | SP2 | SP2-AS1 | SP3 | SP3P | SP4 | SP5 | SP6 | SP7 | SP8 | SP9 | SPA17 | SPAAR | SPACA1 | SPACA3 | SPACA4 | SPACA5 | SPACA6 | SPACA6-AS1 | SPACA7 | SPACA9 | SPACDR | SPAG1 | SPAG11A | SPAG11B | SPAG16 | SPAG16-DT | SPAG17 | SPAG4 | SPAG5 | SPAG5-AS1 | SPAG6 | SPAG7 | SPAG8 | SPAG9 | SPAM1 | SPANXA1 | SPANXA2-OT1 | SPANXB1 | SPANXB2 | SPANXC | SPANXD | SPANXN1 | SPANXN2 | SPANXN3 | SPANXN4 | SPANXN5 | SPARC | SPARCL1 | SPART | SPART-AS1