SOCS4: A promising drug target and biomarker for SH2 domains-containing proteins

Target Name: SOCS4

NCBI ID: G122809

SOCS4

SOCS4: A promising drug target and biomarker for SH2 domains-containing proteins

Abstract:

The protein encoded by the Socs4 gene is a member of the SH2 domain family, which is characterized by a unique combination of amino acid residues that gives them specific structural features and functions. Socs4 is expressed in various cell types and tissues, including the immune system , where it plays a crucial role in regulating immune responses and cell signaling. In this article, we will explore the functions of Socs4 and its potential as a drug target and biomarker.

Introduction:

The protein encoded by the Socs4 gene is a member of the SH2 domain family, which is characterized by a unique combination of amino acid residues that gives them specific structural features and functions. Socs4 is expressed in various cell types and tissues, including the immune system , where it plays a crucial role in regulating immune responses and cell signaling.

SH2 domains:

The SH2 domain is a conserved region of the protein that is characterized by a unique combination of amino acid residues. The SH2 domain is named after the protein encoded by the SH2 gene, which is a key regulator of the immune response. The SH2 domain is composed of several key amino acids, including a double aromatic amino acid (aromatic amino acid), a carboxylic acid, and a hydrogen atom.

Socrs4:

Socrs4 is a 21-kDa protein that is expressed in various cell types, including the immune system. It is characterized by the presence of a SH2 domain and several other conserved amino acids that are typical of SH2 domain-containing proteins. Socrs4

Protein Name: Suppressor Of Cytokine Signaling 4

Functions: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR

The "SOCS4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SOCS4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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