Socs2: A Protein Regulating Sexual Development and Cancer (G8835)

Target Name: SOCS2

NCBI ID: G8835

SOCS2

Socs2: A Protein Regulating Sexual Development and Cancer

Socs2, or sex-selective chromatin-remodeling protein 2, is a protein that plays a crucial role in the regulation of sexual development and fertility in humans. It is a key component of the chromatin complex, which is responsible for ensuring the proper expression of gene during development and reproduction. Socs2 is also involved in the maintenance of genomic stability, and has been linked to various diseases, including cancer.

Socs2 is a protein that consists of 21 kDa of protein and 4 kDa of a N-terminal domain. It is localized to the nuclei of actively transcribing cells, including those of the brain, testes, and ovaries. Socs2 is also expressed in other tissues , including muscle, heart, and liver.

Socs2 is involved in the regulation of gene expression during development and reproduction. It plays a key role in the establishment of a normal sexual identity by ensuring that the correct combination of chromosomes is expressed in the genomes of reproductive cells. During fetal development, Socs2 helps to ensure that the sex chromosomes are properly sorted and that the resulting genomes are stable.

In addition to its role in reproduction, Socs2 is also involved in the regulation of cell growth and differentiation. It has been shown to play a role in the regulation of cell cycle progression, and is involved in the metaphaseG1 checkpoint, which ensures that chromomes are properly organized before the cell divides. Socs2 is also involved in the regulation of cell adhesion, and has been shown to play a role in the development and maintenance of neural cell types.

Socs2 has also been linked to the regulation of cancer. There is evidence to suggest that Socs2 may be involved in the regulation of cell proliferation and the development of cancer. For example, studies have shown that Socs2 levels are increased in various types of cancer, and that inhibiting Socs2 may be a potential therapeutic approach for these diseases.

In conclusion, Socs2 is a protein that is involved in a wide range of cellular processes, including reproduction, growth and differentiation, and cancer. It plays a key role in ensuring the proper expression of genes during development and reproduction, and is potential drug target or biomarker for various diseases. Further research is needed to fully understand the role of Socs2 in these processes, and to determine its potential as a therapeutic approach.

Protein Name: Suppressor Of Cytokine Signaling 2

Functions: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

The "SOCS2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SOCS2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets