SPAG5-AS1: A Potential Drug Target and Biomarker (G100506436)

Target Name: SPAG5-AS1

NCBI ID: G100506436

SPAG5-AS1

Other Name(s): SPAG5 antisense RNA 1 | DKFZp434K129

SPAG5-AS1: A Potential Drug Target and Biomarker

SPAG5-AS1, short for short exon 5 alpha-synuclein, is a protein that is expressed in the brain and has been linked to the development and progression of various neurological disorders, including Alzheimer's disease. The protein is composed of 184 amino acids and has a calculated molecular weight of 21 kDa. It is localized to the endoplasmic reticulum and is predominantly expressed in the brain.

SPAG5-AS1 has been shown to interact with several other proteins, including Tau, a protein that is also associated with the development of Alzheimer's disease. The interaction between SPAG5-AS1 and Tau has been shown to promote the formation of aggregates, which are thought to play a role in the development of neurodegeneration in Alzheimer's disease.

In addition to its interaction with Tau, SPAG5-AS1 has also been shown to interact with several other proteins, including beta-amyloid, a protein that is also thought to contribute to the development of Alzheimer's disease. The interaction between SPAG5-AS1 and beta-amyloid has been shown to promote the formation of amyloid plaques, which are thought to contribute to the development of neurodegeneration in Alzheimer's disease.

SPAG5-AS1 has also been shown to interact with several other proteins that are involved in the development and progression of psychiatric disorders, including depression and anxiety. The interaction between SPAG5-AS1 and these other proteins has been shown to contribute to the development and progression of these disorders.

Despite these promising findings, more research is needed to fully understand the role of SPAG5-AS1 in the development and progression of Alzheimer's disease and other neurological disorders. One potential way to study the role of SPAG5-AS1 is to use it as a drug target. By blocking the interaction between SPAG5-AS1 and other proteins, researchers may be able to develop new treatments for these disorders. Additionally, SPAG5-AS1 may also be used as a biomarker to diagnose and monitor the progression of these disorders.

In conclusion, SPAG5-AS1 is a protein that has been linked to the development and progression of various neurological disorders, including Alzheimer's disease. Its interaction with other proteins, including Tau and beta-amyloid, has been shown to promote the formation of aggregates and the development of neurodegeneration. Additionally, SPAG5-AS1 has also been shown to interact with other proteins that are involved in the development and progression of psychiatric disorders. Further research is needed to fully understand the role of SPAG5-AS1 in these disorders and to develop new treatments and biomarkers for them.

Protein Name: SPAG5 Antisense RNA 1

The "SPAG5-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPAG5-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets