Target Name: TRIM68
NCBI ID: G55128
Review Report on TRIM68 Target / Biomarker Content of Review Report on TRIM68 Target / Biomarker
TRIM68
Other Name(s): tripartite motif-containing protein 68 | TRIM68 variant 1 | RNF137 | E3 ubiquitin-protein ligase TRIM68 | E3 ubiquitin-protein ligase TRIM68 (isoform 1) | Ring finger protein 137 | RING-type E3 ubiquitin transferase TRIM68 | SS56 | Ro/SSA1 related protein | Tripartite motif containing 68, transcript variant 1 | Tripartite motif-containing protein 68 | ring finger protein 137 | MGC126176 | SSA protein SS-56 | OTTHUMP00000230828 | SS-56 | GC109 | Tripartite motif-containing 68 | tripartite motif containing 68 | RING finger protein 137 | OTTHUMP00000230830 | TRI68_HUMAN | FLJ10369

TRIM68: A Potential Drug Target and Biomarker

TRIM68, also known as tripartite motif-containing protein 68, is a protein that is expressed in various tissues and cells of the body. Its function is not well understood, but it is known to play a role in the regulation of cellular processes such as cell adhesion, migration, and invasion. In recent years, researchers have identified TRIM68 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The TRIM68 protein is composed of three distinct domains: an N-terminal transmembrane domain, a coiled-coil domain, and an C-terminal T-cell receptor-like domain. The N-terminal transmembrane domain is responsible for the protein's ability to interact with cell surface receptors, while the coiled-coil domain is responsible for its ability to form inclusion complexes with other proteins. The C-terminal T-cell receptor-like domain is responsible for the protein's ability to interact with the T-cell receptor, which is a protein that plays a critical role in cell signaling and immune responses.

TRIM68 has been shown to be involved in several cellular processes, including cell adhesion, migration, and invasion. Studies have shown that TRIM68 can form inclusion complexes with the protein Shc1, which is a negative regulator of the T-cell receptor. This interaction between TRIM68 and Shc1 suggests that TRIM68 may play a role in regulating T-cell receptor function.

In addition to its role in T-cell receptor function, TRIM68 has also been shown to be involved in the regulation of cell adhesion and migration. Studies have shown that TRIM68 can interact with the protein F-actin, which is involved in cell adhesion and migration. This interaction between TRIM68 and F-actin suggests that TRIM68 may play a role in regulating cell adhesion and migration.

TRIM68 has also been shown to be involved in the regulation of cell signaling pathways that are important for cancer progression. Studies have shown that TRIM68 can interact with the protein PIK3CA, which is a gene that is involved in the regulation of cell signaling pathways. This interaction between TRIM68 and PIK3CA suggests that TRIM68 may play a role in the regulation of cell signaling pathways that are important for cancer progression.

In conclusion, TRIM68 is a protein that is involved in several cellular processes that are important for cell signaling and disease progression. Its potential as a drug target and biomarker makes it an attractive target for researchers to study further. Further studies are needed to fully understand the function of TRIM68 and its potential as a drug target and biomarker.

Protein Name: Tripartite Motif Containing 68

Functions: Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity

The "TRIM68 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRIM68 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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TRIM69 | TRIM7 | TRIM7-AS2 | TRIM71 | TRIM72 | TRIM73 | TRIM74 | TRIM75 | TRIM77 | TRIM8 | TRIM9 | TRIML1 | TRIML2 | TRIO | TRIOBP | TRIP10 | TRIP11 | TRIP12 | TRIP13 | TRIP4 | TRIP6 | Tripartite motif containing 78, pseudogene | TRIQK | TRIR | TRIT1 | TRL-AAG1-2 | TRL-AAG2-3 | TRL-TAG2-1 | TRMO | TRMT1 | TRMT10A | TRMT10B | TRMT10C | TRMT11 | TRMT112 | TRMT12 | TRMT13 | TRMT1L | TRMT2A | TRMT2B | TRMT44 | TRMT5 | TRMT6 | TRMT61A | TRMT61B | TRMT9B | TRMU | TRN-GTT4-1 | TRNA | tRNA splicing endonuclease complex | tRNA(Sec) complex | tRNA-splicing endonuclease complex | tRNA-splicing ligase complex | TRNAU1AP | TRNC | TRND | TRNE | TRNF | TRNG | TRNH | TRNI | TRNK | TRNL1 | TRNL2 | TRNM | TRNN | TRNP | TRNP1 | TRNQ | TRNR | TRNS1 | TRNS2 | TRNT | TRNT1 | TRNV | TRNW | TRNY | TRO | TROAP | TROAP-AS1 | Troponin | TRP-AGG2-5 | TRP-AGG6-1 | TRPA1 | TRPC1 | TRPC2 | TRPC3 | TRPC4 | TRPC4AP | TRPC5 | TRPC6 | TRPC7 | TRPC7-AS1 | TRPM1 | TRPM2 | TRPM2-AS | TRPM3 | TRPM4 | TRPM5 | TRPM6