Target Name: TRPC1
NCBI ID: G7220
Review Report on TRPC1 Target / Biomarker Content of Review Report on TRPC1 Target / Biomarker
TRPC1
Other Name(s): Transient receptor potential canonical 1 | Capacitative calcium channel protein Trp1 | Short transient receptor potential channel 1 (isoform 2) | MGC133335 | Short transient receptor potential channel 1 (isoform 1) | capacitative calcium channel protein Trp1 | Short transient receptor potential channel 1 | HTRP-1 | Transient receptor protein 1 | TRPC1 variant 2 | transient receptor potential cation channel subfamily C member 1 | TRP1 | Transient receptor potential cation channel subfamily C member 1, transcript variant 1 | TRPC1 variant 1 | transient receptor protein 1 | Transient receptor potential cation channel subfamily C member 1, transcript variant 2 | MGC133334 | transient receptor potential canonical 1 | Transient receptor potential cation channel, subfamily C, member 1 | TRP-1 | TRPC1_HUMAN | Transient receptor potential channel 1 | TrpC1

TRPC1: A Protein Targeted for Pain, Inflammation & Fibrosis

TRPC1, Transient receptor potential canonical 1, is a protein that is expressed in many different tissues throughout the body. It is a member of the TRP family of ion channels, which are known for their role in sensory signaling. TRPC1 is primarily expressed in the nervous system, and it is thought to play a role in the detection of pain, inflammation, and other types of injury or stress.

Recent studies have suggested that TRPC1 may be a drug target or biomarker for a variety of diseases. For example, TRPC1 has been shown to be involved in pain perception, and may be a useful target for treatments of chronic pain. Additionally, TRPC1 has been linked to inflammation and fibrosis, and may be a useful biomarker for monitoring the effectiveness of anti-inflammatory treatments.

One of the key challenges in studying TRPC1 is its relatively small size, as proteins with this size tend to be difficult to study. However, researchers have been able to use a variety of techniques to study TRPC1, including immunofluorescence, biochemical assays, and patch-based assays.

One of the most promising aspects of TRPC1 is its potential as a drug target. Researchers have identified several potential drug candidates that target TRPC1, and are in the process of testing them in preclinical studies. These drugs are thought to work by blocking TRPC1's activity, which could lead to the inhibition of pain perception or the regulation of inflammation.

Another potential application of TRPC1 is as a biomarker for monitoring the effectiveness of anti-inflammatory treatments. Inflammation is a complex biological process that can be difficult to study, andTRPC1 may be a useful indicator of the level of inflammation in a patient. By measuring the activity of TRPC1, researchers may be able to determine whether an anti-inflammatory treatment is effective in reducing inflammation.

Overall, TRPC1 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role in the immune system and its potential as a therapeutic agent.

Protein Name: Transient Receptor Potential Cation Channel Subfamily C Member 1

Functions: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion

The "TRPC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRPC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TRPC2 | TRPC3 | TRPC4 | TRPC4AP | TRPC5 | TRPC6 | TRPC7 | TRPC7-AS1 | TRPM1 | TRPM2 | TRPM2-AS | TRPM3 | TRPM4 | TRPM5 | TRPM6 | TRPM7 | TRPM8 | TRPS1 | TRPT1 | TRPV1 | TRPV2 | TRPV3 | TRPV4 | TRPV5 | TRPV6 | TRR-ACG1-2 | TRRAP | TRU-TCA2-1 | TRUB1 | TRUB2 | Trypanosome lytic factor 1 | Trypanosome lytic factor 2 | Trypsin | Tryptase | Tryptophan 5-Monooxygenase | TSACC | TSBP1 | TSBP1-AS1 | TSC1 | TSC2 | TSC22D1 | TSC22D1-AS1 | TSC22D2 | TSC22D3 | TSC22D4 | TSEN15 | TSEN2 | TSEN2P1 | TSEN34 | TSEN54 | TSFM | TSG1 | TSG101 | TSGA10 | TSGA10IP | TSGA13 | TSHB | TSHR | TSHZ1 | TSHZ2 | TSHZ3 | TSHZ3-AS1 | TSIX | TSKS | TSKU | TSLP | TSN | TSNARE1 | TSNAX | TSNAX-DISC1 | TSNAXIP1 | TSPAN1 | TSPAN10 | TSPAN11 | TSPAN12 | TSPAN13 | TSPAN14 | TSPAN15 | TSPAN16 | TSPAN17 | TSPAN18 | TSPAN19 | TSPAN2 | TSPAN3 | TSPAN31 | TSPAN32 | TSPAN33 | TSPAN4 | TSPAN5 | TSPAN6 | TSPAN7 | TSPAN8 | TSPAN9 | TSPEAR | TSPEAR-AS1 | TSPEAR-AS2 | TSPO | TSPO2 | TSPOAP1 | TSPOAP1-AS1