Target Name: PRNP
NCBI ID: G5621
Review Report on PRNP Target / Biomarker Content of Review Report on PRNP Target / Biomarker
PRNP
Other Name(s): AltPrP | Prion protein, transcript variant 2 | PRIP | CD230 antigen | PrP27-30 | PRNP variant 2 | PrPc | GSS | Alternative prion protein (isoform AltPrp) | PRNP variant 1 | Prion protein, transcript variant 3 | Prion-related protein | Major prion protein | prion protein | CJD | ASCR | p27-30 | PrP | PRNP variant 6 | PRNP variant 3 | Alternative prion protein; major prion protein | PrP33-35C | Prion protein, transcript variant 1 | PRIO_HUMAN | KURU | APRIO_HUMAN | Alternative prion protein | prion-related protein | CD230 | Prion protein, transcript variant 6

Unlocking The Potential of PRNP for Neurodegenerative Diseases

PRNP (Pro-Rat Protein Neural Proteins) are a type of protein that is expressed in the brain and other nervous tissue. They are composed of a unique combination of amino acids that gives them their unique structure and function. While PRNP has been studied extensively for many years, there is still much that is not known about this protein.

One of the things that makes PRNP so interesting is its unique structure. PRNP is composed of a series of six transmembrane proteins that are held together by a complex of interactions between their extracellular and intracellular domains. This structure gives PRNP its unique 3D shape, which is important for its function in the nervous system.

One of the key functions of PRNP is its role in neural development and function. PRNP has been shown to play a critical role in the development and maintenance of neural stem cells, which are the foundation of the nervous system. These stem cells are responsible for the growth, differentiation, and repair of neural cells, and they are critical for the development and maintenance of the nervous system.

Another important function of PRNP is its role in neurotransmitter synthesis and release. PRNP is involved in the synthesis and release of several neurotransmitters, including dopamine, serotonin, and GABA. These neurotransmitters are responsible for transmitting signals in the nervous system, and they play a critical role in the regulation of mood, appetite, and other physiological processes.

PRNP is also involved in the regulation of ion channels in the brain. These channels are responsible for the flow of electrical signals through the brain, and they play a critical role in the regulation of muscle contractions, nerve impulse conduction and mood regulation.

In pharmacological studies, PRNP is also considered a potential drug target. The neuromodulatory function of PRNP makes it a research hotspot in the fields of neuroscience and pharmacology. Many studies have explored the potential of PRNP in treating neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and depression.

In addition, PRNP interacts with other molecules in the nervous system. For example, PRNP interacts with receptors on neurons, such as nicotine receptors, cannabinoid receptors, and serotonin receptors. These interactions make PRNPs important prospects in treating addiction and mood disorders.

Overall, PRNP is a very promising drug target. Through in-depth study of the neuromodulatory function of PRNP, better treatments and drugs can be developed that can effectively treat neurodegenerative diseases and improve patients' quality of life.

Protein Name: Prion Protein

The "PRNP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRNP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRNT | Pro-Neuregulin | PROB1 | PROC | PROCA1 | PROCR | PRODH | PRODHLP | Prohibitin | PROK1 | PROK2 | Prokineticin Receptor (PK-R) | PROKR1 | PROKR2 | Prolactin receptor (isoform 1) | Prolyl 4-hydroxylase | PROM1 | PROM2 | PROP1 | Propionyl-CoA Carboxylase | PRORP | PRORSD1P | PRORY | PROS1 | PROS2P | PROSER1 | PROSER2 | PROSER2-AS1 | PROSER3 | Prostaglandin EP Receptor | Prostaglandin synthase | Prostanoid Receptor | Prostanoid TP receptor | Proteasome 20S | Proteasome 26S | Proteasome Complex | Protein arginine N-methyltransferase | Protein disulfide-isomerase | Protein farnesyltransferase | Protein geranylgeranyltransferase type II | Protein kinase C | Protein Kinase D (PKD) | Protein kinase N | Protein NDRG2 (isoform a) | Protein Phosphatase | Protein Phosphatase 2A | Protein Phosphatase 2B | Protein phosphatase 6 | Protein phosphatase-1 | Protein transport protein Sec61 complex | Protein Tyrosine Phosphatase (PTP) | Protein Tyrosine Phosphatase Type IVA | Protein-Synthesizing GTPase (Elongation Factor) | Protocadherin | PROX1 | PROX1-AS1 | PROX2 | PROZ | PRPF18 | PRPF19 | PRPF3 | PRPF31 | PRPF38A | PRPF38B | PRPF39 | PRPF4 | PRPF40A | PRPF40B | PRPF4B | PRPF6 | PRPF8 | PRPH | PRPH2 | PRPS1 | PRPS1L1 | PRPS2 | PRPSAP1 | PRPSAP2 | PRR11 | PRR12 | PRR13 | PRR13P1 | PRR13P3 | PRR14 | PRR14L | PRR15 | PRR15L | PRR16 | PRR18 | PRR19 | PRR20B | PRR20C | PRR20D | PRR21 | PRR22 | PRR23A | PRR23B | PRR23C | PRR23D1 | PRR23E