Ribosomal Protein S7: A Protein Involved in Translation, Stress Response and DNA Replication

Target Name: RPS7

NCBI ID: G6201

RPS7

Ribosomal Protein S7: A Protein Involved in Translation, Stress Response and DNA Replication

Ribosomal protein S7 (RPS7) is a protein that plays a critical role in the process of translation of mRNAs into proteins. It is a large protein that contains multiple domains, including a nucleotide-binding domain, a domain for protein-protein interaction, and a domain for localization to the endoplasmic reticulum (ER). RPS7 is also known as ribosomal protein S7-protein, or P170166.

RPS7 is a protein that is expressed in most eukaryotic cells and is involved in various cellular processes, including protein translation, DNA replication, and stress response. It is a key protein that helps to ensure the accuracy and efficiency of protein translation by serving as a scaffold to hold onto mRNAs during the process of translation.

One of the unique features of RPS7 is its ability to interact with other proteins, including ribosomal protein S10 (RPS10) and the translation factor TFII-3. This interaction between RPS7 and RPS10 is critical for the proper functioning of the ribosome and ensures that mRNAs are properly translated into proteins.

Another important function of RPS7 is its role in stress response. RPS7 is able to interact with the protein heat shock protein HSP70 and can participate in the stress-protein response pathway. This interaction between RPS7 and HSP70 allows RPS7 to help to protect against the effects of stress on the cell and to ensure the stability of the cellular structure.

RPS7 is also involved in the process of DNA replication. It is a protein that is able to interact with the enzyme responsible for DNA replication, called DNA polymerase II (DNA2). This interaction between RPS7 and DNA2 allows RPS7 to help to ensure the accuracy and efficiency of DNA replication and to help to prevent errors in the process.

In addition to its role in cellular processes, RPS7 is also a potential drug target. Its interaction with RPS10 and HSP70 makes it a potential target for small molecules that can modulate these interactions and improve protein translation efficiency. Additionally, RPS7's involvement in stress response and DNA replication also makes it a potential target for drugs that are designed to promote these processes.

Overall, RPS7 is a protein that plays a critical role in cellular processes and is a potential drug target. Further research is needed to fully understand its functions and to develop drugs that can modulate its interactions with other proteins.

Protein Name: Ribosomal Protein S7

Functions: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Required for rRNA maturation (PubMed:19061985). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

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•   general information;
•   protein structure and compound binding;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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