Target Name: ZNF487
NCBI ID: G642819
Review Report on ZNF487 Target / Biomarker Content of Review Report on ZNF487 Target / Biomarker
ZNF487
Other Name(s): KRAB domain only 1 | KRBO1 | ZN487_HUMAN | zinc finger protein 487 | ZNF487P | Putative zinc finger protein 487 | zinc finger protein 487, pseudogene | Putative zinc finger protein 487 isoform 1 | ZNF487 variant 1 | Zinc finger protein 487, transcript variant 1 | KRAB domain only protein 1

ZNF487: A Potential Drug Target and Biomarker

Zinc finger nucleosome (ZFN) proteins are a family of transmembrane proteins that play a crucial role in various cellular processes, including chromatin structure and function, DNA replication, and gene regulation. ZNF487, a member of the ZNF4 family, is a 21-kDa protein that has been identified as a potential drug target and biomarker. In this article, we will explore the molecular structure and function of ZNF487, its potential drug targets, and its potential as a biomarker for various diseases.

Molecular Structure and Function

ZNF487 is a 21-kDa protein that consists of 155 amino acid residues. It has a characteristic ZNF487-specific domain, which is composed of a nucleosome-binding protein (NBP) domain and a C-terminal TAD domain. The NBP domain is responsible for the protein's nuclear localization and functions as a nucleosome-associated protein. The C-terminal TAD domain is a protein-coding region that is involved in protein-protein interactions and is known for its role in regulating protein stability.

The ZNF487 protein is expressed in various tissues and cells, including brain, pancreas, and testes. It is also involved in various cellular processes, including DNA replication, cell division, and cell growth. ZNF487 plays a role in regulating the formation and maintenance of chromatin structures, which are critical for the expression of gene loci and the regulation of cellular processes.

Potential Drug Targets

ZNF487 has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for the development and progression of diseases. One of the potential drug targets for ZNF487 is the regulation of cell growth and differentiation. ZNF487 has been shown to play a role in the regulation of cell proliferation and the maintenance of stem cell properties.

In addition to its role in cell growth and differentiation, ZNF487 has also been shown to be involved in the regulation of cell survival. Studies have shown that ZNF487 plays a role in the regulation of apoptosis, which is a critical mechanism that regulates cell death and has been implicated in various diseases, including cancer.

Another potential drug target for ZNF487 is its role in the regulation of inflammation. ZNF487 has been shown to play a role in the regulation of immune cell function and the regulation of inflammatory responses. This suggests that ZNF487 may be a potential drug target for diseases that are characterized by inflammation and cellular over-response, such as autoimmune diseases and inflammatory bowel diseases.

Potential Biomarkers

ZNF487 has also been identified as a potential biomarker for various diseases. One of the potential benefits of ZNF487 as a biomarker is its ability to be easily measured and to have a long half-life, which allows for its use as a marker for long-term outcomes in clinical trials.

Studies have shown that ZNF487 is involved in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation. This suggests that ZNF487 may be a potential biomarker for diseases that are characterized by these processes, such as cancer, autoimmune diseases, and inflammatory bowel diseases.

Conclusion

In conclusion, ZNF487 is a 21-kDa protein that has been identified as a potential drug target and biomarker. Its characteristic NBP and TAD domains suggest that ZNF487 plays a role in regulating various cellular processes, including cell growth, apoptosis, and inflammation. Further studies are needed to fully understand the function

Protein Name: Zinc Finger Protein 487

Functions: May be involved in transcriptional regulation

The "ZNF487 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF487 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568 | ZNF569 | ZNF56P | ZNF57 | ZNF570 | ZNF571 | ZNF571-AS1 | ZNF572 | ZNF573 | ZNF574 | ZNF575 | ZNF576 | ZNF577 | ZNF578 | ZNF579 | ZNF580 | ZNF582 | ZNF582-DT | ZNF583 | ZNF584 | ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B | ZNF589 | ZNF592 | ZNF593 | ZNF594