TRA2B: A Potential Drug Target in Cell Signaling Pathways (G6434)

Target Name: TRA2B

NCBI ID: G6434

TRA2B

TRA2B: A Potential Drug Target in Cell Signaling Pathways

Protein phosphatase 1 (PP1) is a protein that plays a critical role in cell signaling pathways. It is one of the most widely studied protein in the cell, and various studies have identified it as a potential drug target. One of the subunits of PP1 , known as regulatory subunit 156 (TRA2B), has been identified as a potential drug target in recent years.

TRA2B is a 21-kDa protein that is expressed in various tissues and cells, including brain, heart, and pancreas. It is a key component of the PP1 regulatory complex, which is responsible for regulating protein kinase C (PLC) activity. PLC is a protein that activates the phosphatidylinositol (PIns) signaling pathway, which is involved in various cellular processes, including cell signaling, protein synthesis, and storage.

TRA2B is known for its role in the regulation of PLC activity, and various studies have shown that it plays a critical role in the regulation of protein kinase C activity. PLC activity is regulated by various factors, including PINs, which is a key activator of PLC. Pins can interact with various proteins, including Tra2B, and this interaction is critical for the regulation of PLC activity.

TRA2B is also involved in the regulation of the activity of other enzymes, including the protein kinase A (PKA) and the protein kinase B (PKB). PKA and PKB are also involved in the regulation of PLC activity, and their activity is regulated by various factors, including PIns. PINS can interact with PKA and PKB, and this interaction is critical for the regulation of their activity.

TRA2B is also involved in the regulation of cellular signaling pathways that are involved in various cellular processes, including cell growth, apoptosis, and inflammation. For example, various studies have shown that Tra2B is involved in the regulation of the production of pro-inflammatory cytokines , such as TNF-alpha, IL-1, and IL-6.

TRA2B is also involved in the regulation of the activity of the transcription factor, NF-kappa-B. NF-kappa-B is a protein that plays a critical role in the regulation of various cellular processes, including inflammation, stress, and cell signaling. Tra2B is known for its role in the regulation of NF-kappa-B activity, and various studies have shown that Tra2B interacts with the transcription factor and modulates its activity.

TRA2B is also involved in the regulation of the activity of the protein kinase PDK4. PDK4 is a protein that plays a critical role in the regulation of cell signaling pathways, including cell growth, apoptosis, and angiogenesis. Tra2B is known for its role in the regulation of PDK4 activity, and various studies have shown that Tra2B interacts with the protein and modulates its activity.

TRA2B is also involved in the regulation of the activity of the protein kinase PTEN. PTEN is a protein that plays a critical role in the regulation of various cellular processes, including cell growth, apoptosis, and cancer. Tra2B is known for its role in the regulation of PTEN activity, and various studies have shown that Tra2B interacts with the protein and modulates its activity.

TRA2B is also involved in the regulation of the activity of the protein src. src is a protein that plays a critical role in the regulation of cell signaling pathways, including cell growth, apoptosis, and angiogenesis. Tra2B is known for its role in the regulation of src activity, and various studies have shown that Tra2B interacts with the protein and modulates its activity.

TRA2B is also involved in the regulation of the activity of the protein

Protein Name: Transformer 2 Beta Homolog

Functions: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA

The "TRA2B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRA2B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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