Traf1: A Potential Drug Target and Biomarker (G7185)

Target Name: TRAF1

NCBI ID: G7185

TRAF1

Traf1: A Potential Drug Target and Biomarker

Traf1, short for Tissue-Specific Alkylator, is a protein that is expressed in various tissues of the human body. It is a key regulator of cell division and has been implicated in the development and progression of many diseases. MGC:10353 is a potential drug target or biomarker for Traf1.

Traf1 is a transcription factor that plays a crucial role in the regulation of cell division and cell growth. It is a key regulator of the G1/S transition, which is the stage of cell growth where the cell prepares for cell division. Traf1 helps to ensure that cells enter the G1/S transition at the appropriate time and that they divide at the proper rate.

In addition to its role in cell division, Traf1 is also involved in the regulation of cell growth and cell survival. It has been shown to play a role in the regulation of cell cycle progression, and has been implicated in the development of many diseases.

One of the most promising aspects of Traf1 is its potential as a drug target. Traf1 has been shown to be involved in a wide range of cellular processes, including cell division, cell growth, and cell survival. This makes it an attractive target for drug developers because it is likely that targeting Traf1 may have a broad range of potential therapeutic effects.

In addition to its potential therapeutic effects, Traf1 is also a valuable biomarker for the diagnosis and prognosis of many diseases. Its expression has been shown to be elevated in a wide range of diseases, including cancer, neurodegenerative diseases, and developmental disorders. This makes it a potential biomarker for these diseases and may be useful in the diagnosis and prognosis of these conditions.

Overall, Traf1 is a protein that is expressed in various tissues of the human body and plays a crucial role in the regulation of cell division and cell growth. Its potential as a drug target or biomarker makes it an attractive target for further research and development.

Protein Name: TNF Receptor Associated Factor 1

Functions: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2

The "TRAF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRAF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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