TRAM2: A Potential Drug Target and Biomarker (G9697)

Target Name: TRAM2

NCBI ID: G9697

TRAM2

TRAM2: A Potential Drug Target and Biomarker

TRAM2 (TRAM2_HUMAN), a protein that belongs to the TRAM family, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug candidate has led to a growing body of research.

TRAM2 is a transmembrane protein that is expressed in various tissues and cells throughout the body. Its primary function is to regulate the intracellular signaling pathway known as the TGF-β pathway, which plays a crucial role in cell growth, differentiation, and survival. The The TGF-β pathway is involved in the development and maintenance of tissues and organs, as well as in the regulation of cellular processes such as cell division, migration, and angiogenesis.

TRAM2 is composed of a unique transmembrane domain, a catalytic domain, and an intracellular domain. The transmembrane domain is responsible for maintaining TRAM2's physical stability and functions as a protein that is involved in the regulation of cellular signaling pathways. The catalytic domain is responsible for TRAM2's catalytic activity, which is essential for its function in regulating the TGF-β pathway. The intracellular domain is responsible for TRAM2's ability to interact with other proteins inside the cell.

TRAM2 has been shown to play a role in various cellular processes, including the regulation of cell growth, differentiation, and survival. It has been shown to be involved in the development and maintenance of tissues and organs, as well as in the regulation of cellular processes such as cell division, migration, and angiogenesis.

TRAM2 has also been shown to be involved in the regulation of the TGF-β pathway. The TGF-β pathway is involved in the development and maintenance of tissues and organs, as well as in the regulation of cellular processes such as cell division, migration , and angiogenesis. TRAM2 has been shown to play a role in regulating the TGF-β pathway by interacting with and modulating the activity of the transcription factor, SMAD.

In addition to its role in the TGF-β pathway, TRAM2 has also been shown to be involved in the regulation of cellular processes such as cell adhesion, migration, and survival. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug candidate has led to a growing body of research.

TRAM2 has been shown to be involved in the regulation of cell adhesion and migration. Studies have shown that TRAM2 plays a role in the regulation of cell-cell adhesion by interacting with the adhesion molecule, E-cadherin. This interaction between TRAM2 and E-cadherin has been shown to play a role in the regulation of cell migration and the formation of tissues and organs.

TRAM2 has also been shown to be involved in the regulation of cellular processes such as cell survival. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug candidate has led to a growing body of research.

In conclusion, TRAM2 is a protein that has been shown to play a role in various cellular processes, including the regulation of cell growth, differentiation, and survival. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug candidate has led to a growing body of research. Further research is needed to fully understand the role of TRAM2 in cellular processes and its potential as a drug target.

Protein Name: Translocation Associated Membrane Protein 2

Functions: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293)

The "TRAM2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRAM2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets