A Promising Drug Target (or biomarker) - FNDC4: Unlocking the Mysteries of Inflammatory Diseases

Target Name: FNDC4

NCBI ID: G64838

FNDC4

A Promising Drug Target (or biomarker) - FNDC4: Unlocking the Mysteries of Inflammatory Diseases

introduction

The treatment of inflammatory diseases has always been a research hotspot in the medical field. These diseases are often caused by an overreaction of the immune system, leading to tissue damage and impaired organ function. With the development of medical technology, scientists continue to explore new drug targets in order to provide patients with better treatment options. Today, we are going to discuss a high-profile target鈥擣NDC4.

Discovery and role of FNDC4

FNDC4 is a protein that exists in a variety of immune cells, such as monocytes, T cells, and natural killer cells. FNDC4 plays a key role in inflammatory diseases, and research suggests it may be a potential drug target.

The role of FNDC4 in inflammatory tissues is mainly reflected in the following aspects:

1. Regulate immune cell function: FNDC4 can affect the activity and function of immune cells, such as promoting the activation of T cells and inhibiting the activation of B cells. These effects make FNDC4 a potential therapeutic target.

2. Regulate inflammatory response: FNDC4 participates in the regulation of inflammatory response, including inhibiting the production of inflammatory factors, reducing inflammatory response, etc. These effects make FNDC4 potentially valuable in treating inflammatory diseases.

3. Participate in cell apoptosis: FNDC4 has an apoptotic effect in immune cells and tumor cells, which provides a new idea for inhibiting tumor growth and treating tumors.

4. Participate in immune evasion: FNDC4 has an evasion effect in immune cells, which makes it a potential antigen that can stimulate the immune system to attack tumors. At the same time, FNDC4 may also be involved in the immune evasion of tumor cells and therefore has the potential to treat tumors.

Biological characteristics of FNDC4

As a protein, FNDC4 has a variety of biological characteristics and provides new ideas for studying inflammatory diseases.

1. Expression pattern: FNDC4 is expressed in a variety of immune cells, among which monocytes and T cells have higher expression levels. In inflammatory tissues, the expression level of FNDC4 is significantly increased, which provides a basis for studying the role of FNDC4.

2. Functional domains: FNDC4 has multiple functional domains, including N-terminal 伪-helix, C-terminal 尾-sheet and N-terminal 尾-curl. These structural features may be closely related to the biological functions of FNDC4, providing a structural basis for studying the role of FNDC4.

3. Interaction: FNDC4 interacts with a variety of immune cells and molecules, such as with PD-1, TIM-3 and other molecules. These interactions may be involved in the biological functions of FNDC4, providing new ideas for studying the role of FNDC4.

4. Clinical application prospects: FNDC4 has potential application value in a variety of inflammatory diseases. For example, studies have shown that inhibiting FNDC4 can significantly reduce the symptoms of inflammatory diseases, providing clinical evidence for FNDC4 as a potential drug target.

in conclusion

As a protein, FNDC4 has potential application value in inflammatory diseases. By studying the biological characteristics, functions and interactions of FNDC4, we can reveal the role of FNDC4 in inflammatory diseases and provide new ideas for the treatment of inflammatory diseases. At the same time, FNDC4 may also become a potential drug target, bringing new hope for clinical treatment.

Protein Name: Fibronectin Type III Domain Containing 4

Functions: Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to down-regulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by down-regulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis

The "FNDC4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FNDC4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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