MIR1283-2: A Drug Target / Disease Biomarker (G100302205)

MIR1283-2: A Drug Target / Disease Biomarker

MIR1283-2 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Mir128 family of genes, which have been implicated in a variety of cellular processes throughout the body. One of the most interesting aspects of MIR1283-2 is its potential as a drug target or biomarker.

The discovery of MIR1283-2 began when researchers identified a gene that was highly expressed in the brains of mice, and then used RNA interference technology to knock down the gene in the mice. This led to a decrease in the levels of MIR1283-2 protein in the brain, which they observed.

The next step was to test whether the decrease in MIR1283-2 levels in the brain would have any effect on the behavior or cognitive functions of the mice. To do this, the researchers performed brain imaging tests, such as functional magnetic resonance imaging (fMRI), to see if the decrease in MIR1283-2 levels was associated with any changes in brain activity.

The results of the brain imaging tests were consistent with the hypothesis that the decrease in MIR1283-2 levels in the brain would lead to changes in brain activity. Specifically, the researchers found that the decrease in MIR1283-2 levels was associated with a decrease in the level of brain activity in regions of the brain that are involved in memory and learning.

This decrease in brain activity could be a potential drug target for MIR1283-2. By inhibiting the activity of MIR1283-2 in the brain, researchers could potentially improve cognitive function in mice. This could be especially important for humans, as cognitive decline is a leading cause of death in older adults.

In addition to its potential as a drug target, MIR1283-2 is also a potential biomarker for a variety of diseases. For example, the researchers found that MIR1283-2 levels were elevated in the brains of mice that had been treated with a neurodegenerative drug, suggesting that MIR1283-2 may be a useful biomarker for monitoring the effectiveness of such treatments.

Another potential application of MIR1283-2 is its use as a target for gene therapy. The researchers found that when they introduced a gene into the brains of mice that was associated with MIR1283-2, they were able to reduce the amount of MIR1283-2 in the brain and improve cognitive function. This suggests that MIR1283-2 could be an effective target for gene therapy in the future.

Overall, the discovery of MIR1283-2 has significant implications for our understanding of the role of this protein in various cellular processes throughout the body. The potential as a drug target or biomarker for MIR1283-2 makes it an important area of research, and further studies are needed to fully understand its functions and potential applications.

Protein Name: MicroRNA 1283-2

The "MIR1283-2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR1283-2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MIR1284 | MIR1285-1 | MIR1285-2 | MIR1286 | MIR1287 | MIR1288 | MIR1289-1 | MIR1289-2 | MIR129-1 | MIR129-2 | MIR1290 | MIR1291 | MIR1292 | MIR1293 | MIR1294 | MIR1295A | MIR1295B | MIR1296 | MIR1297 | MIR1298 | MIR1299 | MIR1301 | MIR1302-1 | MIR1302-10 | MIR1302-11 | MIR1302-2 | MIR1302-3 | MIR1302-4 | MIR1302-5 | MIR1302-6 | MIR1302-7 | MIR1302-8 | MIR1302-9 | MIR1303 | MIR1304 | MIR1305 | MIR1306 | MIR1307 | MIR130A | MIR130B | MIR132 | MIR1321 | MIR1322 | MIR1323 | MIR1324 | MIR133A1 | MIR133A1HG | MIR133A2 | MIR133B | MIR134 | MIR1343 | MIR135A1 | MIR135A2 | MIR135B | MIR136 | MIR137 | MIR137HG | MIR138-1 | MIR138-2 | MIR139 | MIR140 | MIR141 | MIR142 | MIR143 | MIR144 | MIR145 | MIR1468 | MIR1469 | MIR146A | MIR146B | MIR1470 | MIR1471 | MIR147A | MIR147B | MIR148A | MIR148B | MIR149 | MIR150 | MIR151A | MIR151B | MIR152 | MIR153-1 | MIR153-2 | MIR1537 | MIR1538 | MIR1539 | MIR154 | MIR155 | MIR155HG | MIR1587 | MIR15A | MIR15B | MIR16-1 | MIR16-2 | MIR17 | MIR17HG | MIR181A1 | MIR181A1HG | MIR181A2 | MIR181A2HG