MIR133A2: A Non-Coding RNA Molecule as A Potential Drug Target and Biomarker
MIR133A2: A Non-Coding RNA Molecule as A Potential Drug Target and Biomarker
MicroRNA 133a-2 (MIR133A2) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. MIR133A2 is a key regulator of cell proliferation and has been shown to play a role in the development and progression of various diseases.
The discovery of MIR133A2 as a potential drug target comes from a study by the research team led by Dr. Qin Liu, a Professor of Chemistry at the University of California, San Diego. The study, published in the journal Nature in 2012, identified MIR133A2 as a negative regulator of the cell cycle, which means that it works to stop the cell cycle when it should have been replicating.
The team also found that MIR133A2 was highly expressed in various cancer tissues, including breast cancer, and that inhibiting the activity of MIR133A2 using small interfering RNA (siRNA) significantly reduced the growth of cancer cells.
Another study by the same research team also found that MIR133A2 was positively correlated with the survival rate of cancer patients. This suggests that MIR133A2 may be a useful biomarker for cancer diagnosis and treatment.
MIR133A2 has also been shown to play a role in the regulation of cell adhesion, which is the process by which cells stick together and form tissues. MIR133A2 has been shown to be involved in the regulation of cell adhesion in various tissues, including brain, heart, and placenta.
The team also found that MIR133A2 was involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. This suggests that MIR133A2 may be a potential drug target for diseases that are characterized by the formation of new blood vessels, such as cancer.
In addition to its potential as a drug target, MIR133A2 has also been shown to be a valuable biomarker for various diseases. The team found that MIR133A2 was highly correlated with the survival rate of patients with various diseases, including cancer. This suggests that MIR133A2 may be a useful biomarker for disease diagnosis and treatment.
In conclusion, MIR133A2 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. The discovery of MIR133A2 comes from a study by the research team led by Dr. Qin Liu, a Professor of Chemistry at the University of California, San Diego. The study identified MIR133A2 as a negative regulator of the cell cycle and found that it was highly expressed in various cancer tissues. The team also found that MIR133A2 was positively correlated with the survival rate of cancer patients and was involved in the regulation of cell adhesion and angiogenesis. These findings suggest that MIR133A2 may be a valuable drug target and biomarker for various diseases.
Protein Name: MicroRNA 133a-2
The "MIR133A2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR133A2 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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MIR133B | MIR134 | MIR1343 | MIR135A1 | MIR135A2 | MIR135B | MIR136 | MIR137 | MIR137HG | MIR138-1 | MIR138-2 | MIR139 | MIR140 | MIR141 | MIR142 | MIR143 | MIR144 | MIR145 | MIR1468 | MIR1469 | MIR146A | MIR146B | MIR1470 | MIR1471 | MIR147A | MIR147B | MIR148A | MIR148B | MIR149 | MIR150 | MIR151A | MIR151B | MIR152 | MIR153-1 | MIR153-2 | MIR1537 | MIR1538 | MIR1539 | MIR154 | MIR155 | MIR155HG | MIR1587 | MIR15A | MIR15B | MIR16-1 | MIR16-2 | MIR17 | MIR17HG | MIR181A1 | MIR181A1HG | MIR181A2 | MIR181A2HG | MIR181B1 | MIR181B2 | MIR181C | MIR181D | MIR182 | MIR1825 | MIR1827 | MIR183 | MIR184 | MIR185 | MIR186 | MIR187 | MIR188 | MIR18A | MIR18B | MIR1908 | MIR1909 | MIR190A | MIR190B | MIR191 | MIR1910 | MIR1911 | MIR1912 | MIR1913 | MIR1914 | MIR1915 | MIR1915HG | MIR192 | MIR193A | MIR193B | MIR193BHG | MIR194-1 | MIR194-2 | MIR194-2HG | MIR195 | MIR196A1 | MIR196A2 | MIR196B | MIR197 | MIR1972-1 | MIR1972-2 | MIR1973 | MIR1976 | MIR198 | MIR199A1 | MIR199A2 | MIR199B | MIR19A
