Target Name: MIR130A
NCBI ID: G406919
Review Report on MIR130A Target / Biomarker Content of Review Report on MIR130A Target / Biomarker
MIR130A
Other Name(s): MicroRNA 130a | hsa-miR-130a-3p | hsa-miR-130a-5p | mir-130a | hsa-mir-130a | miRNA130A | MIRN130A | microRNA 130a

MIR130a: A Non-Coding RNA Molecule Regulating Cellular Processes

MicroRNA (miRNA) 130a is a non-coding RNA molecule that plays a crucial role in regulating various cellular processes in the body. It is made up of 20 amino acid residues and has a unique structure that consists of a stem-loop and a loop region. The stem-loop region is the core of the miRNA and is responsible for coordinating the different regions of the molecule.

MiRNA 130a is a member of the 181-miRNA family, which consists of 200-220 members. These miRNAs are involved in various cellular processes, including cell growth, apoptosis, and metabolism. MIR130a is a well-known miRNA that has been shown to play a role in regulating cell proliferation and has potential as a drug target or biomarker.

One of the key functions of miRNA 130a is its ability to target specific mRNAs for degradation. This is done by binding to the target mRNAs and causing them to be targeted for degradation. This process is known as target-mediated regulation and is a well- established mechanism for miRNA regulation.

MIR130a has been shown to play a role in regulating the expression of various genes, including cancer genes. For example, studies have shown that MIR130a can inhibit the expression of the gene encoding the protein PDGF-尾, which is a key regulator of cell proliferation . This suggests that MIR130a may have potential as a drug target for cancer.

Another function of MIR130a is its role in regulating cell apoptosis. Apoptosis is a natural process that helps the body eliminate damaged or dysfunctional cells. MIR130a has been shown to play a role in regulating cell apoptosis by binding to the protein Bcl-2. Bcl- 2 is a protein that can prevent apoptosis and MIR130a has been shown to inhibit its activity.

MIR130a has also been shown to play a role in regulating cellular metabolism. It has been shown to interact with the protein SIRT1, which is involved in cellular stress response. This interaction suggests that MIR130a may be involved in regulating cellular stress response and metabolism.

MIR130a has a unique structure that consists of a stem-loop and a loop region. The stem-loop region is the core of the miRNA and is responsible for coordinating the different regions of the molecule. The loop region is located at the end of the stem-loop and is responsible for interacting with the target mRNAs.

The miRNA pathway is a complex process that involves the regulation of miRNAs by various factors, including RNA-binding protein (RBP), Argonaute (RISC) RNA-binding protein (RNP), and microRNA-protein interactions (MPI). MIR130a is regulated by these factors and has been shown to play a role in the miRNA pathway.

MIR130a has been shown to have potential as a drug target or biomarker. Studies have shown that MIR130a can inhibit the activity of the drug PDGF-尾, which is a key regulator of cell proliferation. This suggests that MIR130a may have potential as a drug target for cancer. Additionally, MIR130a has been shown to play a role in regulating cell apoptosis and cellular metabolism, which may make it an interesting biomarker for certain diseases.

In conclusion, MIR130a is a well-known miRNA that has been shown to play a role in regulating various cellular processes in the body. Its unique structure and function as a regulator of the miRNA pathway make it a potential drug target or biomarker. Further studies are needed to fully understand the role of MIR130a in cellular processes and its potential as a drug

Protein Name: MicroRNA 130a

The "MIR130A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR130A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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