Target Name: VARS1
NCBI ID: G7407
Review Report on VARS1 Target / Biomarker Content of Review Report on VARS1 Target / Biomarker
VARS1
Other Name(s): VARS2 | Valyl-tRNA synthetase 2 | valRS | Valyl-tRNA synthetase 1 | G7A | VARS | Valyl-tRNA synthetase | valyl-tRNA synthetase 1 | NDMSCA | protein G7a | valine tRNA ligase 1, cytoplasmic | Valine tRNA ligase 1, cytoplasmic | Valine--tRNA ligase | ValRS | Protein G7a | valyl-tRNA synthetase 2 | SYVC_HUMAN

VARS1: A Potential Drug Target and Biomarker for Diseases

VARS1 (VARS2) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and gastrointestinal tract. It is a member of the VAS family, which includes other proteins such as VAS1 and VAS2. The VAS proteins are involved in various physiological processes in the body, including blood vessel formation and maintenance, and have been implicated in a number of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

One of the key functions of VARS1 is its role in blood vessel formation and maintenance. VAS proteins are involved in the formation of blood vessels, as well as the regulation of their diameter and flexibility. This is important for maintaining proper blood flow to the body's various tissues, and is critical for maintaining a healthy immune system.

VARS1 has also been shown to play a role in the regulation of cellular signaling pathways. It has been shown to interact with a variety of signaling molecules, including TGF-β, Wnt, andNotch. These interactions are important for the regulation of cell proliferation, differentiation, and survival.

In addition to its role in blood vessel formation and cellular signaling, VARS1 has also been implicated in the development and progression of a number of diseases. For example, studies have shown that VAS1 is overexpressed in various tissues of cancer, and that it is involved in the regulation of cancer cell growth and survival. Similarly, VAS2 has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease.

Given the numerous roles that VARS1 has been shown to play in various physiological processes, it is a promising target for drug development. Researchers are currently working to identify small molecules that can specifically modulate the activity of VARS1, with the goal of developing new treatments for a variety of diseases.

In addition to its potential as a drug target, VARS1 is also a potential biomarker for a number of diseases. Its expression has been shown to be elevated in a variety of disease states, including cancer, neurodegenerative diseases, and cardiovascular disease. This makes it a promising marker for the diagnosis and treatment of these diseases.

Overall, VARS1 (VARS2) is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role in various physiological processes and its potential as a therapeutic agent.

Protein Name: Valyl-tRNA Synthetase 1

Functions: Catalyzes the attachment of valine to tRNA(Val)

The "VARS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VARS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

VARS2 | Vascular endothelial growth factor receptor (VEGFR) | Vascular endothelial growth factors (VEGF) | VASH1 | VASH1-AS1 | VASH2 | VASN | Vasoactive intestinal polypeptide receptor (VIP-R) | Vasohibin | Vasopressin Receptor | Vasopressin V1 Receptor | VASP | VAT1 | VAT1L | VAV1 | VAV2 | VAV3 | VAV3-AS1 | VAX1 | VAX2 | VBP1 | VCAM1 | VCAN | VCL | VCP | VCPIP1 | VCPKMT | VCX | VCX2 | VCX3A | VCX3B | VCY | VCY1B | VDAC1 | VDAC1P2 | VDAC1P9 | VDAC2 | VDAC2P5 | VDAC3 | VDR | VEGFA | VEGFB | VEGFC | VEGFD | VENTX | VENTXP1 | VENTXP7 | VEPH1 | VEZF1 | VEZT | VGF | VGLL1 | VGLL2 | VGLL3 | VGLL4 | VHL | VIL1 | VILL | VIM | VIP | VIPAS39 | VIPR1 | VIPR1-AS1 | VIPR2 | VIRMA | VIT | VKORC1 | VKORC1L1 | VLDLR | VLDLR-AS1 | VMA21 | VMAC | VMO1 | VMP1 | VN1R1 | VN1R101P | VN1R108P | VN1R10P | VN1R11P | VN1R12P | VN1R17P | VN1R18P | VN1R2 | VN1R4 | VN1R46P | VN1R5 | VN1R82P | VN1R91P | VN1R96P | VN2R11P | VN2R1P | VN2R3P | VNN1 | VNN2 | VNN3P | Voltage-dependent anion channels (Porins) | Voltage-dependent calcium channel gamma subunit | Voltage-gated K(v) channel | Voltage-Gated Sodium Channel Complex | Volume-Regulated Anion Channel (VRAC)