VASP: A Potential Drug Target Or Biomarker (G7408)

Target Name: VASP

NCBI ID: G7408

VASP

Other Name(s): Vasodilator-stimulated phosphoprotein | Vasodilator stimulated phosphoprotein | vasodilator stimulated phosphoprotein | VASP_HUMAN

VASP: A Potential Drug Target Or Biomarker

Vasodilator-stimulated phosphoprotein (VASP) is a protein that is expressed in various tissues of the body, including the heart, lungs, kidneys, and liver. It is a phosphoprotein that is involved in the regulation of blood pressure, and it has been identified as a potential drug target or biomarker.

The Importance of VASP

VASP is a critical regulator of blood pressure, as it helps to maintain the integrity of blood vessels. It does this by controlling the contraction and relaxation of blood vessels, which allows the blood to flow in and out of the body.

VASP is also involved in the regulation of inflammation, as it has been shown to play a role in the inflammatory response. It does this by participating in the production of reactive oxygen species, which can cause damage to tissues if they become too active.

Drug Target or Biomarker?

VASP has been identified as a potential drug target or biomarker due to its involvement in the regulation of blood pressure and inflammation. This is because drugs that target VASP have been shown to be effective in reducing blood pressure and reducing the risk of cardiovascular disease.

One of the drugs that has been shown to target VASP is the Angiotensin-converting enzyme (ACE) inhibitor, which is used to treat hypertension and heart failure. TheACE inhibitor works by blocking the action of angiotensin, a hormone that causes blood vessels to constrict and raise blood pressure.

Another drug that has been shown to target VASP is the ACE inhibitor, \"oseltamivir\" (Tamiflu), which is used to treat influenza (flu). The ACE inhibitor works by blocking the action of angiotensin, which is a hormone that causes blood vessels to constrict and raise blood pressure.

Another potential drug that targets VASP is the sodium channel blocker, \"amlodipine\" (Nifedipine), which is used to treat hypertension and angina. The sodium channel blocker works by blocking the action of sodium channels, which are responsible for the contraction and relaxation of blood vessels.

Conclusion

VASP is a protein that is involved in the regulation of blood pressure and inflammation. It has been identified as a potential drug target or biomarker, and several drugs that target VASP have been shown to be effective in reducing blood pressure and reducing the risk of cardiovascular disease. Further research is needed to fully understand the role of VASP in the regulation of blood pressure and to develop more effective treatments.

Protein Name: Vasodilator Stimulated Phosphoprotein

Functions: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation

The "VASP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VASP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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