Target Name: VN1R1
NCBI ID: G57191
Review Report on VN1R1 Target / Biomarker Content of Review Report on VN1R1 Target / Biomarker
VN1R1
Other Name(s): vomeronasal 1 receptor 1 | Vomeronasal 1 receptor 1 | V1RL1 | Vomeronasal type-1 receptor 1 | hGPCR24 | V3r-related gene protein | V3R-related | VN1R1_HUMAN | V1r-like receptor 1 | V1R-like 1 | G-protein coupled receptor GPCR24 | ZVNR1 | VNR19I1 | vomeronasal olfactory receptor, (chromosome 19) subtype I, member 1 | Vomeronasal olfactory receptor, (chromosome 19) subtype I, member 1 | ZVNH1 | vomeronasal olfactory receptor chromosome 19 subtype I member 1 | Vomeronasal olfactory receptor chromosome 19 subtype I member 1

VN1R1: A Potential Drug Target and Biomarker for Treating Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is a sleep disorder that affects millions of people worldwide, causing breathing to repeatedly stop and start during sleep, leading to disrupted sleep cycles and potentially life-threatening complications. Currently, there are limited treatment options available for this condition, which has led to a growing interest in identifying new drug targets and biomarkers for the development of new therapies. One potential drug target and biomarker for treating OSA is VN1R1, a G protein-coupled receptor located on the surface of neurons in the nervous system.

VN1R1 is a member of the G protein-coupled receptor family, which includes over 700 different receptors that play a critical role in cellular signaling. G protein-coupled receptors are involved in a wide range of physiological processes in the body, including sensory perception, neurotransmitter signaling, and cellular signaling. They are also potential drug targets for a variety of diseases, including OSA.

Recent studies have shown that VN1R1 is involved in the regulation of sleep-wake cycles and breathing movements during sleep. Studies have also demonstrated that individuals with OSA may have increased activity of VN1R1, which could potentially serve as a drug target. By targeting VN1R1, researchers hope to develop new treatments for OSA that can improve sleep quality and reduce the risk of serious complications.

In addition to its potential as a drug target, VN1R1 has also been identified as a potential biomarker for OSA. The detection and quantification of VN1R1 activity has been shown to be reliable and sensitive, making it a promising indicator of the severity of OSA. This may be useful for noninvasive diagnostic tests, such as salivary corticosteroids, which can be used to assess the severity of OSA and guide treatment decisions.

While the potential benefits of targeting VN1R1 with drugs or other therapeutic approaches are significant, it is important to consider the potential risks and challenges as well. One potential risk is the potential for unintended consequences, such as an allergic reaction or an adverse reaction to the drug used. Another risk is the potential for VN1R1 to become resistant to treatment over time, leading to a decrease in effectiveness.

Despite these potential risks, researchers are confident that VN1R1 can be a valuable drug target and biomarker for treating OSA. Further studies are needed to determine the effectiveness of targeting VN1R1 and to develop safe and effective treatments for OSA. By identifying new drug targets and biomarkers for OSA, researchers may be able to develop new treatments that can improve sleep quality and reduce the risk of serious complications associated with this debilitating condition.

Protein Name: Vomeronasal 1 Receptor 1

Functions: Putative pheromone receptor

The "VN1R1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VN1R1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

VN1R101P | VN1R108P | VN1R10P | VN1R11P | VN1R12P | VN1R17P | VN1R18P | VN1R2 | VN1R4 | VN1R46P | VN1R5 | VN1R82P | VN1R91P | VN1R96P | VN2R11P | VN2R1P | VN2R3P | VNN1 | VNN2 | VNN3P | Voltage-dependent anion channels (Porins) | Voltage-dependent calcium channel gamma subunit | Voltage-gated K(v) channel | Voltage-Gated Sodium Channel Complex | Volume-Regulated Anion Channel (VRAC) | VOPP1 | VOR Complex | VPREB1 | VPREB3 | VPS11 | VPS13A | VPS13A-AS1 | VPS13B | VPS13C | VPS13C-DT | VPS13D | VPS16 | VPS18 | VPS25 | VPS26A | VPS26AP1 | VPS26B | VPS26C | VPS28 | VPS29 | VPS33A | VPS33B | VPS35 | VPS35L | VPS36 | VPS37A | VPS37B | VPS37C | VPS37D | VPS39 | VPS41 | VPS45 | VPS4A | VPS4B | VPS50 | VPS51 | VPS51P8 | VPS52 | VPS53 | VPS54 | VPS72 | VPS8 | VPS9D1 | VPS9D1-AS1 | VRK1 | VRK2 | VRK3 | VRTN | VSIG1 | VSIG10 | VSIG10L | VSIG10L2 | VSIG2 | VSIG4 | VSIG8 | VSIR | VSNL1 | VSTM1 | VSTM2A | VSTM2A-OT1 | VSTM2B | VSTM2B-DT | VSTM2L | VSTM4 | VSTM5 | VSX1 | VSX2 | VTA1 | VTCN1 | VTI1A | VTI1B | VTN | VTRNA1-1 | VTRNA1-2 | VTRNA1-3