Target Name: VCL
NCBI ID: G7414
Review Report on VCL Target / Biomarker Content of Review Report on VCL Target / Biomarker
VCL
Other Name(s): vinculin | epididymis secretory sperm binding protein | HEL114 | MVCL | Vinculin, transcript variant 2 | CMD1W | epididymis luminal protein 114 | VINC_HUMAN | vinculin isoform meta-VCL | Metavinculin | Vinculin (isoform meta-VCL) | meta-vinculin | VCL variant 2 | VCL variant 1 | Vinculin (isoform VCL) | MV | CMH15 | Vinculin, transcript variant 1 | Vinculin | metavinculin

VCL: A Protein Involved in Cell Signaling Pathways and Disease Development

VCL (Vinculin) is a protein that is expressed in various tissues throughout the body. It is a key structural component of the cytoskeleton and is involved in the proper functioning of cells. VCL has also been shown to play a role in the regulation of cell growth, differentiation, and survival.

Recent studies have identified VCL as a potential drug target and biomarker for a variety of diseases. One of the main reasons for this is the fact that VCL has been shown to be involved in the regulation of many different signaling pathways that are involved in the development and progression of disease.

One of the key signaling pathways that is involved in VCL is the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cell survival and growth, and is thought to be involved in the development of many different diseases, including cancer.

Research has shown that VCL is involved in the regulation of the PI3K/Akt signaling pathway in a number of ways. For example, studies have shown that VCL can inhibit the activity of the protein kinase Akt, which is a key component of the PI3K/ Akt signaling pathway. This can lead to the inhibition of the signaling pathway and the suppression of cell growth and survival.

Another signaling pathway that is involved in VCL is the TGF-β signaling pathway. This pathway is involved in the regulation of cell growth and differentiation, and is also thought to be involved in the development of many different diseases.

Research has shown that VCL is involved in the regulation of the TGF-β signaling pathway in a number of ways. For example, studies have shown that VCL can inhibit the activity of the protein kinase 5Tf, which is a key component of the TGF- 尾 signaling pathway. This can lead to the inhibition of the signaling pathway and the suppression of cell growth and differentiation.

In addition to its role in the regulation of the PI3K/Akt and TGF-β signaling pathways, VCL has also been shown to be involved in the regulation of cell adhesion. This is the process by which cells stick together and form tissues.

Research has shown that VCL is involved in the regulation of cell adhesion in a number of ways. For example, studies have shown that VCL can interact with the protein cadherin, which is a key component of cell adhesion. This interaction can lead to the regulation of the formation and maintenance of tight junctions, which are the junctions that form between cells.

In conclusion, VCL is a protein that is involved in the regulation of various signaling pathways that are involved in the development and progression of disease. Its role in the regulation of cell growth, differentiation, and survival makes VCL a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of VCL in the regulation of disease.

Protein Name: Vinculin

Functions: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion

The "VCL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VCL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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