VEGFB: Potential Drug Target for Cancer, Heart Disease and Age-Related Conditions

Target Name: VEGFB

NCBI ID: G7423

VEGFB

VEGFB: Potential Drug Target for Cancer, Heart Disease and Age-Related Conditions

VEGFB (Vascular Endothelial Growth Factor B) is a protein that is produced by the endothelial cells, which are the cells that line the blood vessels. The production of VEGFB is critical for the growth and development of blood vessels, and it plays a key role in the regulation of blood flow.

VEGFB has been identified as a potential drug target for a number of diseases, including cancer, heart disease, and age-related diseases. Its role in these conditions is to promote the growth and proliferation of blood vessels, which can lead to the development of new tissues and organs.

One of the key functions of VEGFB is its ability to stimulate the production of new endothelial cells. When a blood vessel is damaged or stressed, VEGFB helps to promote the growth and proliferation of endothelial cells, which can help to repair and regenerate the damaged tissue.

VEGFB has also been shown to play a key role in the regulation of blood pressure. It helps to constrict blood vessels, which can help to lower blood pressure and reduce the risk of cardiovascular disease.

VEGFB is also involved in the development and maintenance of the blood-brain barrier, which is the barrier that separates the brain cells from the blood vessels. This barrier is important for the proper functioning of the brain and is critical for the prevention of brain damage.

VEGFB has been shown to be involved in a number of diseases and disorders, including cancer, heart disease, and age-related diseases. For example, studies have shown that high levels of VEGFB are associated with an increased risk of cancer, and that blocking VEGFB may be a promising strategy for treating this disease.

In addition, VEGFB has also been shown to be involved in a number of other conditions, including:

* The development and maintenance of the blood-brain barrier.
* The regulation of blood pressure.
* The growth and development of tissues and organs.
* The regulation of cell division and growth.

VEGFB is a transmembrane protein, which means that it spans the membrane of the endothelial cells and extends into the surrounding tissue. It is made up of four chains, which are held together by disulfide bonds.

The first chain of VEGFB consists of a pre-尾 chain and a post-尾 chain. The pre-尾 chain is responsible for the formation of the transmembrane region of the protein and is involved in its stability. for the formation of the extracellular domain of the protein and is involved in its function.

The second chain of VEGFB consists of a 纬 chain and a 未 chain. The 纬 chain is responsible for the formation of the transmembrane region and is similar to the pre-尾 chain. The 未 chain is responsible for the formation of the extracellular domain and is similar to the post-尾 chain.

VEGFB is expressed in a variety of tissues and organs, including blood vessels, heart muscle, and brain cells. It is involved in the regulation of blood flow, blood pressure, and cell growth and division.

VEGFB has been shown to have a number of potential therapeutic applications. For example, it has been shown to be involved in the development and progression of cancer, and may be a useful target for cancer therapies.

VEGFB has also been shown to be involved in the regulation of heart disease. Studies have shown that high levels of VEGFB are associated with an increased risk of heart disease, and that blocking VEGFB may be a promising strategy for treating this condition.

VEGFB may also be a useful target for treating age-related diseases, such as Alzheimer's disease and other forms of dementia. Studies have shown that VEGFB is involved in the development and progression of these conditions, and that blocking VEGFB may be a promising strategy

Protein Name: Vascular Endothelial Growth Factor B

Functions: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis

The "VEGFB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VEGFB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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