VIPR2: A GPCR Molecule Regulating Blood Flow To The Digestive Tract

Target Name: VIPR2

NCBI ID: G7434

VIPR2

VIPR2: A GPCR Molecule Regulating Blood Flow To The Digestive Tract

VIPR2 (Vasoactive Intestinal Research Cell 2) is a protein that is expressed in the enteric nervous system (ENS) and is involved in the regulation of blood flow to the digestive tract. It is a G protein-coupled receptor (GPCR), which means that it interacts with intracellular signaling molecules called G proteins. This protein has been shown to play a role in the development and maintenance of cardiovascular disease, and is also a potential drug target.

VIPR2 is a member of the VIPR family of GPCRs, which includes proteins that are involved in the regulation of neural circuits in the brain and body. The VIPR2 gene was identified in 2004, and it is located on chromosome 11.2.

Function and localization

VIPR2 is a 21-kDa protein that is expressed in the enteric nervous system (ENS) of higher animals, including humans. It is primarily located in the distal portion of the small intestine, where it is involved in the regulation of blood flow to the digestive tract.

VIPR2 is a GPCR, which means that it interacts with intracellular signaling molecules called G proteins. G proteins are a family of transmembrane proteins that play a critical role in intracellular signaling. They are composed of a catalytic active protein subunit and a transmembrane protein subunit that interacts with the intracellular signaling molecules.

VIPR2 is shown to play a role in the regulation of neural circuits in the brain and body. It is involved in the development and maintenance of cardiovascular disease, and is also a potential drug target.

Drug targeting

VIPR2 is a potential drug target because of its involvement in the regulation of cardiovascular disease. Cardiovascular disease is a leading cause of death in adults, and it is a complex condition that is characterized by the development of atherosclerotic plaque in the arterial system.

Studies have shown that VIPR2 is involved in the regulation of cardiovascular disease by controlling the diameter of blood vessels and the formation of new blood vessels. VIPR2 has also been shown to play a role in the regulation of blood pressure, which is another risk factor for cardiovascular disease.

In addition to its involvement in cardiovascular disease, VIPR2 may also be a potential biomarker for the disease. The development and progression of cardiovascular disease is a complex process that is influenced by many factors, including genetic and environmental factors.

By targeting VIPR2, researchers may be able to identify new diagnostic or therapeutic approaches for cardiovascular disease. This could lead to the development of more effective treatments for this complex and deadly condition.

Conclusion

VIPR2 is a protein that is involved in the regulation of blood flow to the digestive tract. It is a GPCR and plays a role in the development and maintenance of cardiovascular disease. It is also a potential drug target and may be a biomarker for the disease . Further research is needed to fully understand the role of VIPR2 in cardiovascular disease and to develop effective treatments for this complex condition.

Protein Name: Vasoactive Intestinal Peptide Receptor 2

Functions: This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C

The "VIPR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VIPR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets