Target Name: ZNF226
NCBI ID: G7769
Review Report on ZNF226 Target / Biomarker Content of Review Report on ZNF226 Target / Biomarker
ZNF226
Other Name(s): ZNF226 variant 1 | Kruppel-associated box protein | Zinc finger protein 226 (isoform a) | zinc finger protein 226 | ZN226_HUMAN | Zinc finger protein 226 | Zinc finger protein 226, transcript variant 1

ZNF226: A Potential Drug Target for Neurodevelopmental Disorders

ZNF226 (ZNF226 variant 1) is a gene that encodes for a protein known as ZNF2, which is a key regulator of neural development and function. The ZNF2 gene has been implicated in a number of neurodevelopmental disorders, including Down syndrome, mental retardation, and addiction.

The ZNF2 gene has four splice variants, including ZNF226, which is the most abundant and well-studied variant. ZNF226 is a 21-kDa protein that is expressed in a variety of tissues, including brain, heart, and muscle. It is involved in the regulation of neural stem cell proliferation, differentiation, and survival, and is thought to play a role in the development and maintenance of neural tissue homeostasis.

ZNF226 has been shown to be involved in a number of neural development and function processes, including neuron specification, synaptic plasticity, and stress response. It has been shown to play a role in the regulation of neuronal excitability and in the modulation of neural circuits.

In addition to its role in neural development and function, ZNF226 has also been shown to be involved in the regulation of cellular processes such as cell adhesion, migration, and survival. It has been shown to play a role in the regulation of angiogenesis, the formation of new blood vessels, and in the regulation of tissue repair.

Given its involvement in a number of neural development and function processes, ZNF226 has been considered as a potential drug target or biomarker for a variety of neurodevelopmental disorders. For example, ZNF226 has been shown to be downregulated in individuals with Down syndrome, and it has been suggested that targeting ZNF226 may be a potential treatment for this disorder. Similarly, ZNF226 has been shown to be involved in the regulation of addiction, and it has been suggested that targeting ZNF226 may be a potential treatment for addiction.

In conclusion, ZNF226 is a gene that has been implicated in a number of neurodevelopmental disorders, including Down syndrome and addiction. The ZNF2 gene has four splice variants, including ZNF226, and research has suggested that targeting ZNF226 may be a potential treatment for these disorders. Further research is needed to fully understand the role of ZNF226 in neural development and function, as well as its potential as a drug target or biomarker.

Protein Name: Zinc Finger Protein 226

Functions: May be involved in transcriptional regulation

The "ZNF226 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF226 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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