Target Name: ZNF341
NCBI ID: G84905
Review Report on ZNF341 Target / Biomarker Content of Review Report on ZNF341 Target / Biomarker
ZNF341
Other Name(s): HIES3 | ZNF341 variant 2 | Zinc finger protein 341 (isoform 2) | ZN341_HUMAN | Zinc finger protein 341, transcript variant 2 | Zinc finger protein 341 | zinc finger protein 341

ZNF341 Regulates HSC Proliferation and Immune Function

ZNF341 (HIES3), a gene that encodes for a protein known as p180, is a key regulator of the hematopoietic stem cell (HSC) proliferation and differentiation. The HSC is a vital cell that produces all blood cells, including red blood cells, white blood cells, and platelets. HSC proliferation and differentiation are critical for the maintenance of blood cell production and may be regulated by various signaling pathways. The p180 protein has been shown to play a crucial role in regulating HSC proliferation and differentiation, and is therefore a potential drug target or biomarker for the treatment of various hematological and cardiovascular diseases.

The p180 protein is a transcription factor that was identified as a potential drug target in the 1990s due to its involvement in the regulation of cell proliferation and survival. The protein is expressed in various tissues and cells, including the brain, spinal cord, heart, and liver. It has been shown to play a role in the regulation of cell cycle progression, apoptosis, and angiogenesis.

ZNF341 (HIES3) is a key regulator of HSC proliferation and differentiation, and has been shown to promote the proliferation of HSCs in both in vitro and in vivo models. The protein has been shown to enhance the expression of genes involved in cell growth, apoptosis, and angiogenesis, such as the TGF-β transcription factor and the Runx genes.

In addition to its role in HSC proliferation, ZNF341 (HIES3) has also been shown to play a role in the regulation of immune cell function. The protein has been shown to enhance the production of immune cells, such as natural killer cells and T cells, and to regulate their proliferation and differentiation.

ZNF341 (HIES3) has also been shown to play a role in the regulation of cellular signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cell survival and growth, and has been implicated in various diseases, including cancer and cardiovascular disease.

In conclusion, ZNF341 (HIES3) is a protein that has been shown to play a crucial role in the regulation of HSC proliferation and differentiation, and has potential as a drug target or biomarker for the treatment of various hematological and cardiovascular diseases. Further research is needed to fully understand the role of this protein in cellular signaling pathways and its potential as a therapeutic agent.

Protein Name: Zinc Finger Protein 341

Functions: Transcriptional activator of STAT3 involved in the regulation of immune homeostasis. Also able to activate STAT1 transcription

The "ZNF341 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF341 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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