ZNF253: A Protein Targeted for Cancer and Other Diseases (G56242)
ZNF253: A Protein Targeted for Cancer and Other Diseases
ZNF253 (ZNF411) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ZNF family of proteins, which are known for their role in regulating gene expression and cell development. ZNF253 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, ZNF253 has become a focus of interest for researchers and pharmaceutical companies looking for new treatments for these diseases.
One of the key functions of ZNF253 is its role in regulating the activity of genes that are involved in cell growth and division. This protein helps to ensure that the cell cycle is properly regulated, which is essential for the development and growth of tissues and organs. ZNF253 has been shown to play a role in the regulation of the cyclin D1 gene, which is involved in the G1 phase of the cell cycle.
In addition to its role in cell growth and division, ZNF253 has also been shown to play a role in the regulation of cell survival. This protein helps to ensure that cells are able to survive and divide in an environment that is hostile to them, such as the inside of the body. ZNF253 has been shown to play a role in the regulation of the survival and proliferation of various types of cancer cells, including breast, ovarian, and colorectal cancer cells.
Another function of ZNF253 is its role in the regulation of cellular processes that are important for the development and maintenance of tissues and organs. This protein helps to ensure that cells are able to migrate and differentiate into the correct type of cell, which is essential for the development and growth of tissues and organs. ZNF253 has been shown to play a role in the regulation of the migration and differentiation of various types of cells, including blood cells, nerve cells, and muscle cells.
In addition to its role in the regulation of cell survival and migration, ZNF253 has also been shown to play a role in the regulation of the immune system. This protein helps to ensure that the immune system is able to function properly and protect the body against harmful substances and diseases. ZNF253 has been shown to play a role in the regulation of the development and function of immune cells, including natural killer cells and T-cells.
Given its role in so many important cellular processes, it is not surprising that ZNF253 has become a drug target for various pharmaceutical companies. Many of these companies are working on developing drugs that can inhibit the activity of ZNF253 in order to treat diseases that are caused by the over-expression or dysfunction of this protein. These drugs may work by inhibiting the activity of ZNF253, or by interacting with it in a way that disrupts its normal function.
One of the challenges in developing drugs that target ZNF253 is the fact that this protein is involved in many different cellular processes, and it is not clear exactly how inhibiting its activity will have the desired therapeutic effect. In order to overcome this challenge, researchers are using a variety of techniques to study the behavior of ZNF253 in different cellular contexts. These studies are providing valuable insights into the mechanisms of ZNF253's function and the potential targets for its inhibition.
Another challenge in developing drugs that target ZNF253 is the fact that this protein is expressed in many different tissues and organs, which makes it difficult to predict how a drug will be able to affect its expression and function in different tissues. In order to address this challenge, researchers are using techniques such as RNA interference and gene editing to
Protein Name: Zinc Finger Protein 253
Functions: May function as a transcription factor. Seem to have a transcriptional repression activity
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• general information;
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• protein biological mechanisms;
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• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
ZNF254 | ZNF256 | ZNF257 | ZNF26 | ZNF260 | ZNF263 | ZNF264 | ZNF266 | ZNF267 | ZNF268 | ZNF271P | ZNF273 | ZNF274 | ZNF275 | ZNF276 | ZNF277 | ZNF28 | ZNF280A | ZNF280B | ZNF280C | ZNF280D | ZNF281 | ZNF282 | ZNF283 | ZNF284 | ZNF285 | ZNF285CP | ZNF286A | ZNF286B | ZNF287 | ZNF292 | ZNF295-AS1 | ZNF296 | ZNF3 | ZNF30 | ZNF300 | ZNF300P1 | ZNF302 | ZNF304 | ZNF311 | ZNF316 | ZNF317 | ZNF318 | ZNF319 | ZNF32 | ZNF32-AS1 | ZNF32-AS2 | ZNF32-AS3 | ZNF320 | ZNF321P | ZNF322 | ZNF322P1 | ZNF324 | ZNF324B | ZNF326 | ZNF329 | ZNF330 | ZNF331 | ZNF333 | ZNF334 | ZNF335 | ZNF337 | ZNF33A | ZNF33B | ZNF33BP1 | ZNF34 | ZNF341 | ZNF341-AS1 | ZNF343 | ZNF345 | ZNF346 | ZNF347 | ZNF35 | ZNF350 | ZNF350-AS1 | ZNF354A | ZNF354B | ZNF354C | ZNF355P | ZNF358 | ZNF362 | ZNF365 | ZNF366 | ZNF367 | ZNF37A | ZNF37BP | ZNF382 | ZNF383 | ZNF384 | ZNF385A | ZNF385B | ZNF385C | ZNF385D | ZNF385D-AS1 | ZNF385D-AS2 | ZNF391 | ZNF394 | ZNF395 | ZNF396 | ZNF397
