Stable Interaction with Other Proteins: A Key Feature of ZNF32-AS1
Stable Interaction with Other Proteins: A Key Feature of ZNF32-AS1
ZNF32-AS1 (bA402L1.8), a protein that belongs to the Zinc Finger Nucleotide (ZFN) family, plays a crucial role in the regulation of cellular processes. ZNF32-AS1 is expressed in various tissues and has been implicated in the development and progression of various diseases, including cancer.
The ZNF32-AS1 protein is composed of a unique fusion protein that consists of a ZNF32 gene, a short nuclear glycolic acid (AS1), and a ZNF31 gene. ZNF32-AS1 is expressed in various tissues, including brain, heart, liver, and stem cells. It is expressed in a highly variable manner, with different levels of expression depending on the specific cell type and the context in which it is expressed.
One of the unique features of ZNF32-AS1 is its ability to form a stable interaction with other proteins. ZNF32-AS1 can form a complex with various transcription factors, including NF-kappa-B, AP-1, and STAT3. These interactions play a critical role in the regulation of cellular processes, including cell growth, apoptosis, and inflammation.
ZNF32-AS1 has also been shown to play a role in the regulation of gene expression. It can interact with specific DNA sequences and influence the activity of transcription factors. For example, studies have shown that ZNF32-AS1 can interact with the AS1 region of the transcription factor ASXL and influence its activity.
In addition to its role in gene expression, ZNF32-AS1 has also been shown to play a critical role in the regulation of cellular processes that are important for the survival of cancer cells. For example, studies have shown that ZNF32-AS1 can inhibit the inhibition of cell apoptosis by the transcription factor p53, which is a critical factor in the regulation of cell death.
The high level of expression of ZNF32-AS1 makes it an attractive drug target. Drugs that target ZNF32-AS1 have been shown to have a therapeutic effect on various diseases, including cancer. For example, a drug called Fasoraptanib has been shown to inhibit the activity of ZNF32-AS1 and to have therapeutic effects on cancer cells.
In addition to its potential therapeutic effects, ZNF32-AS1 is also a potential biomarker for the diagnosis and monitoring of various diseases. The expression of ZNF32-AS1 has been shown to be affected by various diseases, including cancer, and it has been used as a biomarker for the diagnosis and monitoring of these diseases.
Overall, ZNF32-AS1 is a protein that has critical roles in the regulation of cellular processes and has been implicated in the development and progression of various diseases. Its unique ability to form stable interactions with other proteins and its role in the regulation of gene expression make it an attractive drug target and a potential biomarker for the diagnosis and monitoring of these diseases. Further research is needed to fully understand the functions of ZNF32-AS1 and its potential as a drug and biomarker.
Protein Name: ZNF32 Antisense RNA 1
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More Common Targets
ZNF32-AS2 | ZNF32-AS3 | ZNF320 | ZNF321P | ZNF322 | ZNF322P1 | ZNF324 | ZNF324B | ZNF326 | ZNF329 | ZNF330 | ZNF331 | ZNF333 | ZNF334 | ZNF335 | ZNF337 | ZNF33A | ZNF33B | ZNF33BP1 | ZNF34 | ZNF341 | ZNF341-AS1 | ZNF343 | ZNF345 | ZNF346 | ZNF347 | ZNF35 | ZNF350 | ZNF350-AS1 | ZNF354A | ZNF354B | ZNF354C | ZNF355P | ZNF358 | ZNF362 | ZNF365 | ZNF366 | ZNF367 | ZNF37A | ZNF37BP | ZNF382 | ZNF383 | ZNF384 | ZNF385A | ZNF385B | ZNF385C | ZNF385D | ZNF385D-AS1 | ZNF385D-AS2 | ZNF391 | ZNF394 | ZNF395 | ZNF396 | ZNF397 | ZNF398 | ZNF402P | ZNF404 | ZNF407 | ZNF407-AS1 | ZNF408 | ZNF41 | ZNF410 | ZNF414 | ZNF415 | ZNF416 | ZNF417 | ZNF418 | ZNF419 | ZNF420 | ZNF423 | ZNF425 | ZNF426 | ZNF428 | ZNF429 | ZNF43 | ZNF430 | ZNF431 | ZNF432 | ZNF433 | ZNF433-AS1 | ZNF436 | ZNF436-AS1 | ZNF438 | ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467
