Target Name: ZNF230
NCBI ID: G7773
Review Report on ZNF230 Target / Biomarker Content of Review Report on ZNF230 Target / Biomarker
ZNF230
Other Name(s): zinc finger protein FDZF2 | Zinc finger protein 230 | ZN230_HUMAN | zinc finger protein 230 | FDZF2 | Zinc finger protein FDZF2

ZNF230: A Potential Drug Target and Biomarker for Autism

Introduction

Autism is a neurodevelopmental disorder that affects millions of people worldwide, characterized by persistent difficulties in social interaction, communication, and repetitive behaviors. Although the exact cause of autism is still unknown, research has identified genetic and environmental factors that contribute to its development. One of the genetic factors that has been identified is the zinc finger protein (ZNF230), a protein that plays a crucial role in the development and maintenance of neuronal structure and function. ZNF230 has also been implicated in the etiology of autism, and as such, it has emerged as a potential drug target and biomarker for the disorder.

ZNF230: Structure and Function

ZNF230 is a member of the ZNF family of proteins, which are known for their ability to regulate gene expression and DNA replication. ZNF230 is characterized by a zinc finger domain, which consists of four conserved amino acids that are responsible for the protein's unique structure and function. The zinc finger domain is a common feature of many proteins that plays a role in the regulation of gene expression, and is thought to function as a structural scaffold that helps to maintain the stability and accessibility of the protein's functional domains.

ZNF230 is also characterized by a N-terminus that is rich in basic amino acids, as well as a C-terminus that is rich in acidic amino acids. The N-terminus of ZNF230 is involved in the formation of a complex with other proteins, while the C-terminus is involved in the regulation of ZNF230's stability and localization to the cell membrane.

Function

Several studies have demonstrated the role of ZNF230 in the development and maintenance of neuronal structure and function. In addition to its role in regulating gene expression, ZNF230 is also involved in the regulation of DNA replication, cell growth, and the establishment of neuronal connections.

One of the most significant functions of ZNF230 is its role in the regulation of neuronal cell proliferation. ZNF230 has been shown to play a positive role in the regulation of neuronal cell proliferation, and is thought to do so by regulating the activity of the transcription factor , Numb. Numb is a protein that is known to play a role in the regulation of neuronal cell proliferation, and ZNF230 has been shown to work with Numb to promote the growth and survival of neuronal cells.

In addition to its role in cell proliferation, ZNF230 is also involved in the regulation of neuronal connectivity. ZNF230 has been shown to play a role in the regulation of the trafficking of synaptic vesicles, which are responsible for the transfer of electrical signals between neurons. ZNF230 has also been shown to work with the protein, Calbindin, to regulate the formation and stability of synaptic vesicles, which is thought to play a role in the regulation of neuronal communication.

Disease association

The zinc finger protein (ZNF230) has been implicated in the development and maintenance of several neurological disorders, including autism. Several studies have demonstrated the role of ZNF230 in the development of autism, and as such, it has emerged as a potential drug target and biomarker for the disorder.

One of the most significant findings of recent studies is the involvement of ZNF230 in the regulation of the oxidation stress response, a response that is thought to play a role in the development of neurodegenerative diseases, including autism. Several studies have shown that ZNF230 is involved in the regulation of the oxidation stress response, and that its activity is disrupted in individuals with autism.

In addition to its involvement in the regulation of the oxidation stress response, ZNF230 is also thought to play a role in the regulation of

Protein Name: Zinc Finger Protein 230

Functions: May be involved in transcriptional regulation

The "ZNF230 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF230 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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