ZNF251: A Potential Drug Target and Biomarker for Various Diseases
ZNF251: A Potential Drug Target and Biomarker for Various Diseases
ZNF251 (ZN251_HUMAN), a protein encoded by the Zinc Finger N-Code gene (ZNF251), is a key regulator of cellular processes that are essential for various physiological functions in the human body. ZNF251 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
The ZNF251 gene is located on chromosome 16p31 and encodes a protein with 251 amino acid residues. The protein has a unique structure that consists of a N-terminal zinc finger domain, a central 尾-sheet, and a C-terminal T-loop. The zinc finger domain is a well-known structural motif that is characterized by a specific arrangement of amino acids, typically four conserved amino acids (in the case of ZNF251, Glu-21, Lys-22, Asp-23, and Glu-24 ).
ZNF251 is involved in various cellular processes that are critical for normal development, growth, and function. One of its key functions is to regulate the expression of genes involved in the cell cycle, apoptosis, angiogenesis, and inflammation. ZNF251 has been shown to play a role in the regulation of cell cycle progression, and it has been shown to interact with various cellular signaling pathways, including the TGF-β pathway.
In addition to its role in cell cycle regulation, ZNF251 is also involved in the regulation of cell apoptosis. Apoptosis is a critical mechanism that helps cells to eliminate themselves when they are no longer needed or when their damaged state has reached a threshold. ZNF251 has has been shown to regulate the execution of apoptotic events, including the production of pro-apoptotic proteins and the regulation of apoptosis-associated genes.
ZNF251 has also been shown to be involved in the regulation of angiogenesis, the process by which new blood vessels are formed in the body. Angiogenesis is a critical process that is required for the development and maintenance of tissues and organs, and it is highly regulated by various factors, including Wnt signaling, Hedgehog signaling, and Notch signaling. ZNF251 has been shown to play a role in the regulation of angiogenesis by promoting the production of endothelial cells and the formation of blood vessels.
In addition to its involvement in cell apoptosis and angiogenesis, ZNF251 has also been shown to be involved in the regulation of inflammation. Inflammation is a critical immune response that is essential for the maintenance of tissue health, but it can also contribute to the development and progression of various diseases, including cancer. ZNF251 has been shown to regulate the production of pro-inflammatory cytokines, such as TNF-伪 and IL-6, and to regulate the regulation of immune cells, such as natural killer cells and T cells.
Given its involvement in so many critical cellular processes, ZNF251 is a potential drug target and biomarker for various diseases. For example, ZNF251 has been shown to be involved in the regulation of cancer cell growth and progression, and it has been identified as a potential therapeutic target for various types of cancer, including breast, ovarian, and prostate cancer. In addition, ZNF251 has been shown to be involved in the regulation of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, and it has been identified as a potential therapeutic target for these conditions.
ZNF251 is also a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, ZNF251 has been shown to be involved in the regulation of cancer cell proliferation, and its levels have been shown to be affected by various types of cancer, including breast, ovarian, and prostate cancer. In addition, ZNF251 has
Protein Name: Zinc Finger Protein 251
Functions: May be involved in transcriptional regulation
The "ZNF251 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF251 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
ZNF252P | ZNF252P-AS1 | ZNF253 | ZNF254 | ZNF256 | ZNF257 | ZNF26 | ZNF260 | ZNF263 | ZNF264 | ZNF266 | ZNF267 | ZNF268 | ZNF271P | ZNF273 | ZNF274 | ZNF275 | ZNF276 | ZNF277 | ZNF28 | ZNF280A | ZNF280B | ZNF280C | ZNF280D | ZNF281 | ZNF282 | ZNF283 | ZNF284 | ZNF285 | ZNF285CP | ZNF286A | ZNF286B | ZNF287 | ZNF292 | ZNF295-AS1 | ZNF296 | ZNF3 | ZNF30 | ZNF300 | ZNF300P1 | ZNF302 | ZNF304 | ZNF311 | ZNF316 | ZNF317 | ZNF318 | ZNF319 | ZNF32 | ZNF32-AS1 | ZNF32-AS2 | ZNF32-AS3 | ZNF320 | ZNF321P | ZNF322 | ZNF322P1 | ZNF324 | ZNF324B | ZNF326 | ZNF329 | ZNF330 | ZNF331 | ZNF333 | ZNF334 | ZNF335 | ZNF337 | ZNF33A | ZNF33B | ZNF33BP1 | ZNF34 | ZNF341 | ZNF341-AS1 | ZNF343 | ZNF345 | ZNF346 | ZNF347 | ZNF35 | ZNF350 | ZNF350-AS1 | ZNF354A | ZNF354B | ZNF354C | ZNF355P | ZNF358 | ZNF362 | ZNF365 | ZNF366 | ZNF367 | ZNF37A | ZNF37BP | ZNF382 | ZNF383 | ZNF384 | ZNF385A | ZNF385B | ZNF385C | ZNF385D | ZNF385D-AS1 | ZNF385D-AS2 | ZNF391 | ZNF394
