Target Name: ZNF26
NCBI ID: G7574
Review Report on ZNF26 Target / Biomarker Content of Review Report on ZNF26 Target / Biomarker
ZNF26
Other Name(s): HEL-179 | zinc finger protein KOX20 | KOX20 | Zinc finger protein KOX20 | Zinc finger protein 26 | epididymis luminal protein 179 | Zinc finger protein 26 isoform 1 precursor (isoform 1) | ZNF26 variant 1 | Zinc finger protein 26 precursor | Zinc finger protein 26, transcript variant 1 | zinc finger protein 26

ZNF26: Potential Therapeutic Targets and Biomarkers for Various Diseases

ZNF26 (HEL-179) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ZNF2 family of proteins, which are known for their role in regulating gene expression and cell proliferation. ZNF26 is highly expressed in the human placenta, and has been shown to play a role in the development and maintenance of placenta-tissue interactions.

Recent studies have suggested that ZNF26 may be a drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because ZNF26 has been shown to interact with a wide range of molecules, including transcription factors, signaling molecules, and cytokines. These interactions may regulate the expression of genes that are involved in the development and progression of these diseases.

One potential mechanism by which ZNF26 may be involved in the development of cancer is by promoting the growth and survival of cancer cells. ZNF26 has been shown to stimulate the growth of various types of cancer cells in cell culture and animal models. It has also been shown to promote the migration of cancer cells to new sites of growth. These findings suggest that ZNF26 may be a useful target for cancer therapies that aim to inhibit cell proliferation or migration.

Another potential mechanism by which ZNF26 may be involved in the development and progression of neurodegenerative diseases is by contributing to the neurodegeneration that these diseases cause. ZNF26 has been shown to interact with various neurotransmitter systems, including dopamine, norepinephrine, and serotonin. These interactions may regulate the expression of genes involved in neurotransmission and may contribute to the neurodegeneration that these diseases cause.

In addition, ZNF26 has also been shown to be involved in the regulation of inflammation. This is important because inflammation is a key feature of many neurodegenerative diseases, including Alzheimer's disease. ZNF26 has been shown to interact with various signaling molecules, including TLR2 and NF-kappa-B. These interactions may regulate the expression of genes involved in inflammation and may contribute to the development and progression of neurodegenerative diseases.

Overall, ZNF26 is a protein that has important roles in regulating gene expression and cell proliferation. The potential targets and biomarkers for ZNF26, as well as its potential therapeutic applications, are an exciting area of research that may have implications for the treatment of various diseases.

Protein Name: Zinc Finger Protein 26

Functions: May be involved in transcriptional regulation

The "ZNF26 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF26 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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