ADIPOR2: A Potential Drug Target and Biomarker (G79602)

Target Name: ADIPOR2

NCBI ID: G79602

ADIPOR2

ADIPOR2: A Potential Drug Target and Biomarker

Adiponectin receptor protein 2 (ADIPOR2) is a protein that is expressed in various tissues throughout the body, including adipose tissue, bone marrow, and the brain. It is a member of the superfamily of C-type lectins, which are a group of transmembrane proteins that play a critical role in cell-cell and cell-extracellular matrix interactions. One of the unique features of ADIPOR2 is its ability to interact with adiponectin, a hormone that is produced by the body and plays a crucial role in regulating energy metabolism.

The interaction between ADIPOR2 and adiponectin is a critical process that helps to regulate various physiological processes in the body, including weight loss, bone density, and inflammation. In obesity, the increased levels of adiponectin can lead to a decrease in the activity of ADIPOR2, which can lead to an increase in the production of fat and a worsening of various health conditions such as obesity, type 2 diabetes, and cardiovascular disease.

As a potential drug target, ADIPOR2 has been identified as a promising target for the development of anti-obesity and anti-inflammatory drugs. Studies have shown that inhibiting the activity of ADIPOR2 can lead to a decrease in the production of fat and an improvement in various health indicators.

In addition to its potential as a drug target, ADIPOR2 has also been identified as a potential biomarker for various diseases. The level of ADIPOR2 is often decreased in individuals with obesity, which can be used as a diagnostic marker for obesity. Additionally, ADIPOR2 has been shown to be involved in the regulation of bone density, which is an important predictor of osteoporosis.

In conclusion, ADIPOR2 is a protein that plays a critical role in various physiological processes in the body, including energy metabolism and inflammation. Its interaction with adiponectin makes it a potential drug target for the development of anti-obesity and anti-inflammatory drugs. Additionally, its potential as a biomarker for various diseases makes it an attractive target for researchers to study the role of this protein in human health and disease. Further research is needed to fully understand the role of ADIPOR2 in the regulation of energy metabolism and inflammation, and to develop effective treatments for obesity and other diseases.

Protein Name: Adiponectin Receptor 2

Functions: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity)

The "ADIPOR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ADIPOR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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