GKAP1 Regulates Pain Perception, Neurotransmitter Signaling and BBB Function

Target Name: GKAP1

NCBI ID: G80318

GKAP1

GKAP1 Regulates Pain Perception, Neurotransmitter Signaling and BBB Function

GKAP1 (GKAP42) is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and kidneys. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a key role in cellular signaling.

GKAP1 is known for its role in the regulation of pain perception and neurotransmitter signaling. It is a potent antagonist of the neurotransmitter pain-causing neurotransmitter, serotonin, and has been shown to reduce the pain sensation in animal models of pain testing.

GKAP1 is also known to play a role in the regulation of the blood-brain barrier (BBB), which is a specialized barrier that separates the brain from the blood and lymphatic system. The BBB is designed to protect the brain from harmful substances and to allow only certain substances to enter and exit the brain. GKAP1 is known to modulate the BBB and is involved in the regulation of neurotransmitter signaling.

In addition to its role in pain perception and neurotransmitter signaling, GKAP1 is also known to play a role in the regulation of inflammation and cellular signaling. It is a potent inhibitor of the pro-inflammatory molecule, nuclear factor kappa B (NF-kappa-B) , and has been shown to have anti-inflammatory effects in animal models of inflammation.

GKAP1 is also known for its role in the regulation of cell survival and proliferation. It is a potent inhibitor of the protein, p53, which is known for its role in cell growth and apoptosis. GKAP1 has been shown to protect cells from the effects of p53 and has been shown to play a role in the regulation of cell survival and proliferation.

GKAP1 is also known for its role in the regulation of the nervous system. It is a potent modulator of the neurotransmitter, dopamine, and has been shown to play a role in the regulation of movement and motivation. GKAP1 has also been shown to play a role in the regulation of neurotransmitter signaling in the brain and has been shown to modulate the activity of neural circuits.

GKAP1 is also known for its role in the regulation of the immune system. It is a potent inhibitor of the immune response and has been shown to play a role in the regulation of inflammation and immune cell function. GKAP1 has also been shown to play a role in the regulation of cell death in the immune system and has been shown to protect immune cells from stress-induced cell death.

GKAP1 is also known for its role in the regulation of the endocrine system. It is a potent inhibitor of the hormone, cortisol, and has been shown to play a role in the regulation of stress response and inflammation. a role in the regulation of hormone signaling in the endocrine system and has been shown to protect endocrine cells from stress-induced cell death.

GKAP1 is also known for its role in the regulation of the cell signaling pathway known as the TGF-β pathway. This pathway is involved in the regulation of cell growth, apoptosis, and inflammation. GKAP1 is known to play a role in the regulation of TGF-β signaling and has been shown to play a role in the regulation of cell growth, apoptosis, and inflammation.

GKAP1 is also known for its role in the regulation of the protein, TrkB. TrkB is a key component of the TGF-β pathway and is involved in the regulation of cell growth, apoptosis, and

Protein Name: G Kinase Anchoring Protein 1

Functions: Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation

The "GKAP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GKAP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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