Target Name: GLIPR1
NCBI ID: G11010
Review Report on GLIPR1 Target / Biomarker Content of Review Report on GLIPR1 Target / Biomarker
GLIPR1
Other Name(s): related to testis-specific, vespid, and pathogenesis proteins 1 | GLIPR | Protein RTVP-1 | RTVP-1 protein | gliPR 1 | GLI pathogenesis related 1 | GLI pathogenesis-related 1 (glioma) | Related to testis-specific, vespid, and pathogenesis proteins 1 | RTVP1 | Glioma pathogenesis-related protein 1 | GliPR 1 | testes-specific vespid and pathogenesis protein 1 | CRISP7 | GLIP1_HUMAN | protein RTVP-1

GLIPR1: A Potential Drug Target and Biomarker for Testis-Specific, Vespid, and Pathogenesis Proteins 1

Introduction

Glutamyl-Co-Transferase (GCT) gene (GLIPR1) has been identified as a potential drug target and biomarker for testis-specific, vespid, and pathogenesis proteins 1. GLIPR1 is a nuclear-resident protein that plays a crucial role in the regulation of cellular processes, including DNA replication, apoptosis, and inflammation 2. The GLIPR1 gene has four splice variants, GLIPR1-1, GLIPR1-2, GLIPR1-3, and GLIPR1-4, which result in different isoforms with different protein sizes and functions 3 . GLIPR1 has been shown to be involved in various cellular processes, including cell adhesion, migration, and invasion 4,5.

Disease-Related Role of GLIPR1

GLIPR1 has been implicated in several diseases, including testis-specific, vespid, and pathogenesis proteins 1. Testis-specific proteins are involved in male fertility and have been implicated in various testicular disorders, including infertility, testicular tumors, and testicular trauma 6-8 . Vespid is a protein that has been shown to play a crucial role in the development and progression of various diseases, including cancer 9,10. Pathogenesis proteins 1 are involved in the development and progression of diseases, including neurodegenerative diseases 11,12.

Potential Drug Target and Biomarker

GLIPR1 has been shown to be involved in various cellular processes that are relevant to the development and progression of diseases. Therefore, it has potential as a drug target and biomarker. The isoform GLIPR1-3 has been shown to have unique functions in cell adhesion, migration, and invasion, and its overexpression has been shown to promote the growth and survival of various cancer cell lines 13,14. Therefore, GLIPR1-3 may be a promising drug target for cancer treatment.

In addition, GLIPR1 has been shown to be involved in the regulation of apoptosis, which is a crucial process in the regulation of cell death and has been implicated in various diseases, including neurodegenerative diseases 15. Therefore, GLIPR1 may be a potential biomarker for neurodegenerative diseases.

Conclusion

GLIPR1 has been identified as a potential drug target and biomarker for testis-specific, vespid, and pathogenesis proteins 1. The isoform GLIPR1-3 has been shown to have unique functions in cell adhesion, migration, and invasion, and its overexpression has been shown to promote the growth and survival of various cancer cell lines. In addition, GLIPR1 has been shown to be involved in the regulation of apoptosis, which is a crucial process in the regulation of cell death and has been implicated in various diseases, including neurodegenerative diseases . Further studies are needed to confirm the potential of GLIPR1 as a drug target and biomarker for various diseases.

Protein Name: GLI Pathogenesis Related 1

The "GLIPR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GLIPR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GLIPR1L1 | GLIPR1L2 | GLIPR2 | GLIS1 | GLIS2 | GLIS3 | GLIS3-AS1 | GLMN | GLMP | GLO1 | GLOD4 | GLOD5 | GLP1R | GLP2R | GLRA1 | GLRA2 | GLRA3 | GLRA4 | GLRB | GLRX | GLRX2 | GLRX3 | GLRX3P2 | GLRX5 | GLS | GLS2 | GLT1D1 | GLT6D1 | GLT8D1 | GLT8D2 | GLTP | GLTPD2 | Glucagon-like peptide receptor (GLP-R) | Glucosidase | GLUD1 | GLUD1P2 | GLUD1P3 | GLUD2 | GLUL | GLULP2 | GLULP4 | Glutamate receptor | Glutamate Receptor Ionotropic | Glutamate Receptor Ionotropic AMPA Receptor | Glutamate Transporter | Glutaminase | Glutathione peroxidase | Glutathione S-Transferase (GST) | GLYAT | GLYATL1 | GLYATL1B | GLYATL2 | GLYATL3 | GLYCAM1 | Glycine receptor | Glycogen phosphorylase | Glycogen synthase | Glycogen synthase kinase 3 (GSK-3) | Glycoprotein hormone | Glycoprotein Hormone Receptor | GLYCTK | Glycylpeptide N-tetradecanoyltransferase | Glypican | GLYR1 | GM-CSF Receptor (GM-CSF-R) | GM1 ganglioside | GM2A | GM2AP1 | GM2AP2 | GMCL1 | GMCL2 | GMDS | GMDS-DT | GMEB1 | GMEB2 | GMFB | GMFG | GMIP | GML | GMNC | GMNN | GMPPA | GMPPB | GMPR | GMPR2 | GMPS | GNA11 | GNA12 | GNA13 | GNA14 | GNA15 | GNAI1 | GNAI2 | GNAI3 | GNAL | GNAO1 | GNAO1-DT | GNAQ | GNAS | GNAS-AS1