GLRA2: A Potential Drug Target and Biomarker for Glycine Receptor Alpha 2

Target Name: GLRA2

NCBI ID: G2742

GLRA2

GLRA2: A Potential Drug Target and Biomarker for Glycine Receptor Alpha 2

Glycine receptor alpha 2 (GLRA2), also known as Glycine receptor alpha 2 subunit (GLRA2-SU), is a protein that plays a crucial role in cellular signaling. GLRA2 is a type I transmembrane protein that is expressed in various tissues, including the brain, pancreas, and gastrointestinal tract. It is a potential drug target and biomarker for various diseases, including diabetes, cancer, and neurodegenerative disorders.

GLRA2 is involved in multiple cellular signaling pathways, including the regulation of pain, inflammation, and neurotransmitter signaling. It is a key receptor for the neurotransmitter glycine, which is a naturally occurring compound that has been shown to have anti-inflammatory and neuroprotective effects.

GLRA2 has been shown to be involved in the regulation of pain perception and neurotransmission. For example, GLRA2 has been shown to play a role in the regulation of pain sensitivity in animals, with studies suggesting that GLRA2 may be involved in the modulation of pain perception. Additionally, GLRA2 has been shown to be involved in the regulation of neurotransmitter release and signaling in the brain, including the regulation of neurotransmitter receptor function.

GLRA2 has also been shown to be involved in the regulation of inflammation and cellular immune response. For example, GLRA2 has been shown to play a role in the regulation of inflammation in response to tissue damage or infection, as well as in the regulation of cellular immune response.

GLRA2 is also involved in the regulation of cellular adhesion and migration, as well as in the regulation of cell survival and proliferation. For example, GLRA2 has been shown to play a role in the regulation of cell adhesion and migration, as well as in the regulation of cell survival and proliferation.

GLRA2 has been shown to be involved in the regulation of various physiological processes, including sleep and appetite. For example, GLRA2 has been shown to play a role in the regulation of sleep-wake cycle in animals, with studies suggesting that GLRA2 may be involved in the modulation of sleep-wake cycle. Additionally, GLRA2 has been shown to play a role in the regulation of appetite and metabolism in animals, with studies suggesting that GLRA2 may be involved in the regulation of appetite and metabolism.

GLRA2 has also been shown to be involved in the regulation of various diseases, including diabetes, cancer, and neurodegenerative disorders. For example, GLRA2 has been shown to be involved in the regulation of insulin sensitivity and glucose metabolism in diabetes, with studies suggesting that GLRA2 may be involved in the modulation of insulin sensitivity and glucose metabolism. Additionally, GLRA2 has been shown to play a role in the regulation of cancer cell growth and metastasis, with studies suggesting that GLRA2 may be involved in the regulation of cancer cell growth and metastasis. Finally, GLRA2 has been shown to play a role in the regulation of neurodegenerative disorders, with studies suggesting that GLRA2 may be involved in the regulation of neurodegenerative disorders.

In conclusion, GLRA2 is a protein that is involved in multiple cellular signaling pathways that are important for cellular function and health. GLRA2 has been shown to play a role in the regulation of pain, inflammation, neurotransmission, and cellular immune response, as well as in the regulation of sleep, appetite, and cellular adhesion and migration. Additionally, GLRA2 has been shown to be involved in the regulation of various diseases, including diabetes, cancer, and neurodegenerative disorders. Given its involvement in multiple cellular signaling pathways, GLRA2 may be a valuable drug target and biomarker for a variety of diseases.

Protein Name: Glycine Receptor Alpha 2

Functions: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:15302677, PubMed:16144831, PubMed:23895467, PubMed:25445488, PubMed:26370147). Channel opening is also triggered by taurine and beta-alanine (PubMed:15302677). Plays a role in synaptic plasticity (By similarity). Contributes to the generation of inhibitory postsynaptic currents, and is involved in the down-regulation of neuronal excitability (PubMed:25445488). Plays a role in cellular responses to ethanol (PubMed:23895467)

The "GLRA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GLRA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets