GLYAT: A Key Enzyme in the Glycine Cycle (G10249)

Target Name: GLYAT

NCBI ID: G10249

GLYAT

GLYAT: A Key Enzyme in the Glycine Cycle

GLYAT (Glycine N-acyltransferase (isoform b)) is a protein that is expressed in various tissues and cells in the human body. It is a key enzyme in the glycine cycle, a process that is involved in the metabolism of proteins and other molecules. GLYAT is responsible for transferring a specific amino acid, glycine, to another amino acid via a series of chemical reactions.

The glycine cycle is a critical process for the body to maintain proper protein synthesis and to repair damaged proteins. It is also involved in the production of other important molecules, such as neurotransmitters and hormones. GLYAT is a key enzyme in the glycine cycle because it is responsible for the final step in the cycle, where the amino acid glycine is transferred to another amino acid via a chemical reaction.

GLYAT is a protein that is expressed in various tissues and cells in the human body, including the brain, heart, and kidneys. It is also expressed in various types of cancer, including breast, ovarian, and prostate cancer. The exact function of GLYAT is not yet well understood, but it is thought to be involved in the regulation of protein synthesis and metabolism.

One of the key potential applications of GLYAT is as a drug target. By inhibiting the activity of GLYAT, researchers may be able to reduce the production of proteins that are involved in cancer growth and progression. This could be a useful way to treat various types of cancer.

Another potential application of GLYAT is as a biomarker. By measuring the level of GLYAT in tissues and cells, researchers may be able to monitor the effectiveness of treatments for various types of cancer. This could be a useful way to determine the effectiveness of new treatments and to identify potential drug targets.

In conclusion, GLYAT is a protein that is expressed in various tissues and cells in the human body. It is a key enzyme in the glycine cycle and is involved in the production of important molecules in the body. While the exact function of GLYAT is not yet well understood, it is thought to be involved in the regulation of protein synthesis and metabolism. GLYAT is a potential drug target and could also be used as a biomarker in the treatment of various types of cancer. Further research is needed to fully understand the role of GLYAT in the body and to develop new treatments based on its properties.

Protein Name: Glycine-N-acyltransferase

Functions: Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid

The "GLYAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GLYAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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