GMCL1: A Protein Implicated in Cell Signaling and Fibrosis (G64395)

Target Name: GMCL1

NCBI ID: G64395

GMCL1

GMCL1: A Protein Implicated in Cell Signaling and Fibrosis

GMCL1 (also known as BTBD13) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the G protein-coupled receptor (GPCR) family, which is a large family of transmembrane proteins that play a key role in cellular signaling.

GMCL1 is known for its role in the regulation of inflammation and immune responses. It is expressed in high levels in the liver and other tissues, and has been shown to play a key role in the development of liver fibrosis. Fibrosis is the excessive accumulation of extracellular matrix (ECM) components in tissues, which can lead to the loss of tissue function and increased risk of disease.

In addition to its role in fibrosis, GMCL1 has also been shown to play a key role in the regulation of inflammation. It is a potent negative regulator of the transcription factor Nrf2, which is known for its role in the regulation of DNA damage repair and inflammation. Nrf2 is a transcription factor that is activated in response to DNA damage or other stressors, and has been shown to play a key role in the regulation of immune and inflammatory responses.

GMCL1 has also been shown to play a key role in the regulation of cell survival. It is a positive regulator of the survival signaling pathway, which is a network of signals that promote cell survival in response to stressors such as UV radiation, nutrient deprivation, and radiation. The survival signaling pathway is a critical pathway that is involved in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

GMCL1 is also involved in the regulation of cellular signaling in the regulation of cell-cell adhesion. It is a negative regulator of the cadherin gene, which is known for its role in the regulation of cell-cell adhesion. Cadherins are a family of transmembrane proteins that are involved in cell-cell adhesion, and are critical for the regulation of tissue structure and organization.

In addition to its role in cell signaling, GMCL1 is also involved in the regulation of cellular processes such as cell migration and the regulation of neurotransmitter release. It is a positive regulator of the migration of neurons, and is involved in the regulation of neurotransmitter release. from neuron cells.

GMCL1 is a protein that has been shown to play a key role in the regulation of various cellular processes in the body. It is a potential drug target (or biomarker) due to its involvement in the regulation of inflammation, immune responses, cell survival, and cell-cell adhesion. Further research is needed to fully understand the role of GMCL1 in the regulation of cellular processes and its potential as a drug target.

Protein Name: Germ Cell-less 1, Spermatogenesis Associated

Functions: Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity)

The "GMCL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GMCL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets