Target Name: LBH
NCBI ID: G81606
Review Report on LBH Target / Biomarker Content of Review Report on LBH Target / Biomarker
LBH
Other Name(s): MGC163287 | Protein LBH | hLBH | DKFZp566J091 | MGC104312 | OTTHUMP00000201113 | OTTHUMP00000201112 | limb bud and heart development homolog | Limb bud and heart development protein homolog | limb bud and heart development protein homolog | LBH_HUMAN | LBH regulator of WNT signaling pathway

LBH: A Protein Involved in GPCR Signaling and Potential Drug Target

LBH, also known as MGC163287, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the G protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling.

One of the unique features of LBH is its ability to interact with several different GPCR tyros, which are the protein molecules that receive the signals from the neurotransmitters that are released by the brain. This interactivity makes LBH an attractive target for the development of new drugs for a variety of neurological and psychiatric disorders, including depression, anxiety, and schizophrenia.

In addition to its potential as a drug target, LBH is also a potential biomarker for certain neurological disorders. For example, studies have shown that LBH levels are often reduced in individuals with depression, and that this reduction is associated with increased symptoms of the disease. Additionally, LBH has been shown to be involved in the regulation of neural circuits, which could provide insight into the underlying mechanisms of certain psychiatric disorders.

The ability of LBH to interact with multiple GPCR tyros makes it an intriguing candidate for drug development. GPCR tyros are involved in a wide range of signaling pathways, including sensory perception, neurotransmission, and cellular signaling. By targeting these tyros, drugs can modulate the activity of the neurons and neural circuits that are involved in the development of certain psychiatric and neurological disorders.

In addition to its potential as a drug target, LBH is also a potential biomarker for certain disorders. For example, studies have shown that LBH levels are often reduced in individuals with depression, and that this reduction is associated with increased symptoms of the disease. Additionally, LBH has been shown to be involved in the regulation of neural circuits, which could provide insight into the underlying mechanisms of certain psychiatric disorders.

The GPCR family of proteins is involved in a wide range of signaling pathways in the body, and the role of LBH in these pathways is still being fully understood. However, studies have shown that LBH plays an important role in the regulation of neural circuits, which are responsible for transmitting signals between neurons and neural circuits.

In addition to its potential role in neural circuits, LBH is also involved in the regulation of the immune system. For example, studies have shown that LBH is involved in the regulation of the production of immune cells that are responsible for fighting off infections. Additionally, LBH has been shown to be involved in the regulation of the inflammatory response, which could have implications for the development of certain inflammatory neurological disorders.

Overall, LBH is a protein that is expressed in various tissues of the body and is involved in a wide range of signaling pathways in the body. Its ability to interact with multiple GPCR tyros makes it an attractive target for the development of new drugs for a variety of neurological and psychiatric disorders. In addition to its potential as a drug target, LBH is also a potential biomarker for certain disorders and is involved in the regulation of neural circuits, immune system, and inflammatory response. Further research is needed to fully understand the role of LBH in the regulation of neural circuits and the development of certain psychiatric and neurological disorders.

Protein Name: LBH Regulator Of WNT Signaling Pathway

Functions: Transcriptional activator which may act in mitogen-activated protein kinase signaling pathway

The "LBH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LBH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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LBHD1 | LBP | LBR | LBX1 | LBX1-AS1 | LBX2 | LBX2-AS1 | LCA5 | LCA5L | LCAL1 | LCAT | LCDR | LCE1A | LCE1B | LCE1C | LCE1D | LCE1E | LCE1F | LCE2A | LCE2B | LCE2C | LCE2D | LCE3A | LCE3B | LCE3C | LCE3D | LCE3E | LCE4A | LCE5A | LCE6A | LCIIAR | LCK | LCLAT1 | LCMT1 | LCMT2 | LCN1 | LCN10 | LCN12 | LCN15 | LCN1P1 | LCN1P2 | LCN2 | LCN6 | LCN8 | LCN9 | LCNL1 | LCOR | LCORL | LCP1 | LCP2 | LCT | LCT-AS1 | LCTL | LDAF1 | LDAH | LDB1 | LDB2 | LDB3 | LDC1P | LDHA | LDHAL6A | LDHAL6B | LDHAL6CP | LDHAP5 | LDHB | LDHBP1 | LDHC | LDHD | LDLR | LDLRAD1 | LDLRAD2 | LDLRAD3 | LDLRAD4 | LDLRAP1 | LDOC1 | LEAP2 | LECT2 | LEF1 | LEF1-AS1 | LEFTY1 | LEFTY2 | LEKR1 | LELP1 | LEMD1 | LEMD1-AS1 | LEMD2 | LEMD3 | LENEP | LENG1 | LENG8 | LENG8-AS1 | LENG9 | LEO1 | LEP | LEPR | LEPROT | LEPROTL1 | LERFS | LETM1 | LETM2