Target Name: STK40
NCBI ID: G83931
Review Report on STK40 Target / Biomarker Content of Review Report on STK40 Target / Biomarker
STK40
Other Name(s): STK40_HUMAN | Serine/threonine kinase 40, transcript variant 3 | serine/threonine kinase 40 | Ser/Thr-like kinase | Serine/threonine-protein kinase 40 (isoform 2) | SgK495 | Serine/threonine-protein kinase 40 | sugen kinase 495 | Serine/threonine kinase 40 | SHIK | Sugen kinase 495 | SINK-homologous serine/threonine-protein kinase | STK40 variant 3 | RP11-268J15.4 | 2310004N11Rik

STK40: A Potential Cancer Therapeutic?

STK40 (STK40_HUMAN), also known as human STK40, is a protein that is expressed in various tissues and cells of the human body. It is a non-coding RNA molecule that is composed of 1,184 amino acids. STK40 is involved in the regulation of various cellular processes, including cell growth, differentiation, and DNA replication.

One of the unique features of STK40 is its ability to interact with the protein p53, which is a well-known tumor suppressor protein. This interaction between STK40 and p53 has led to the hypothesis that STK40 may be a drug target or biomarker for various types of cancer.

In cancer, the regulation of STK40 expression and activity is often disrupted, which can lead to the development and progression of cancer. Therefore, targeting STK40 with drugs or other therapeutic agents may be a promising strategy for the treatment of cancer.

STK40 has been shown to be involved in the regulation of various cellular processes, including cell growth, differentiation, and DNA replication. It has been shown to play a role in the regulation of cell cycle progression, and it has been shown to interact with the protein p53.

In addition to its role in cell cycle regulation, STK40 has also been shown to be involved in the regulation of cell survival. This is because STK40 has been shown to play a role in the regulation of apoptosis, which is a process by which cells undergo programmed cell death.

STK40 has also been shown to be involved in the regulation of cellular signaling pathways. This is because it has been shown to interact with various signaling proteins, including TGF-β1, which is a protein that plays a role in cell signaling.

In conclusion, STK40 is a protein that has been shown to be involved in various cellular processes, including cell growth, differentiation, and DNA replication. It has also been shown to interact with the protein p53, which is a well-known tumor suppressor protein . These properties make STK40 a promising drug target or biomarker for various types of cancer. Further research is needed to fully understand the role of STK40 in cancer development and treatment.

Protein Name: Serine/threonine Kinase 40

Functions: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription

The "STK40 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about STK40 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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