A closer look at SUGCT: The potential drug target (or biomarker) of SUGCT (SUCHY_HUMAN)

Target Name: SUGCT

NCBI ID: G79783

SUGCT

A closer look at SUGCT: The potential drug target (or biomarker) of SUGCT (SUCHY_HUMAN)

Introduction

SUGCT (SUCHY_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. Its function is not well understood, but research has shown that it plays a significant role in several physiological processes, including cell signaling, inflammation, and fibrosis. As a result, SUGCT has been identified as a potential drug target or biomarker. In this article, we will provide a closer look at SUGCT, its function, and its potential as a drug target.

Function and localization

SUGCT is a 21-kDa protein that is expressed in the brain, heart, and kidneys. It is highly conserved across different species, and its amino acid sequence is similar to that of other evolutionarily conserved proteins, such as the heat shock protein (Hsp ) family.SUGCT is primarily localized to the cytoplasm of cells, and its concentration is highest in brain and heart cells.

Functional insights

SUGCT has been shown to play a role in several physiological processes. One of its most well-known functions is its role in cell signaling. SUGCT has been shown to interact with several signaling pathways, including the TGF-β pathway, the Wnt pathway, and the FGF pathway. These interactions have been shown to regulate various cellular processes, including cell growth, differentiation, angiogenesis, and inflammation.

In addition to its role in cell signaling, SUGCT has also been shown to play a role in inflammation. Research has shown that SUGCT has been shown to contribute to the regulation of inflammatory responses, and it has been shown to interact with several factors involved in inflammation. , including nuclear factor kappa B (NFKB), which is a well-known regulator of inflammation.

Fibrosis is another process that in which SUGCT has been shown to play a role. Fibrosis is a complex process that involves the regulation of cell proliferation, differentiation, and extracellular matrix (ECM) formation. SUGCT has been shown to contribute to the regulation of these processes, and it has been shown to interact with several factors involved in fibrosis, including the transcription factor Smad2.

Drug targeting

SUGCT has been identified as a potential drug target due to its unique function and its involvement in several physiological processes. One of the most promising strategies for targeting SUGCT is the use of small molecules that can modulate its activity. Several small molecules have been shown to interact with SUGCT and to modulate its function, including inhibitors of the protein kinase kinase (PKG) pathway, which is a well-known regulator of cell signaling.

Another approach to targeting SUGCT is the use of antibodies that can recognize and bind to its specific epitope. This approach has been shown to be effective in targeting SUGCT and modulating its function. Antibody-based approaches have been shown to be effective in treating a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Conclusion

SUGCT is a protein that has been shown to play a role in several physiological processes, including cell signaling, inflammation, and fibrosis. As a result, it has been identified as a potential drug target or biomarker. Further research is needed to fully understand its function and its potential as a drug target. By targeting SUGCT with small molecules or antibodies, we may be able to modulate its activity and treat a variety of diseases.

Protein Name: Succinyl-CoA:glutarate-CoA Transferase

Functions: Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate

The "SUGCT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SUGCT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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