Target Name: STMN3
NCBI ID: G50861
Review Report on STMN3 Target / Biomarker Content of Review Report on STMN3 Target / Biomarker
STMN3
Other Name(s): SCG10-like-protein | SCLIP | OTTHUMP00000031570 | Stathmin-3 (isoform 1) | STMN3 variant 1 | STMN3_HUMAN | SCG10-like protein | stathmin 3 | Stathmin 3, transcript variant 1 | Stathmin-3 | stathmin-like 3

STMN3: A Potential Drug Target in The CNS

Synaptic Transmission Model (STMN3) is a protein that is expressed in high levels in the central nervous system (CNS) and is involved in the transmission of signals between neurons. The STMN3 protein is also known as SCG10-like-protein and has been identified as a potential drug target in the CNS.

The STMN3 protein is composed of 155 amino acid residues and has a calculated molecular weight of 19.5 kDa. It is expressed in the CNS and is found in the postsynaptic terminal of neurons, where it is involved in the regulation of synaptic strength and neurotransmitter release.

The STMN3 protein is known to play a role in the transmission of signals between neurons in the CNS. It is involved in the regulation of neurotransmitter release and has been shown to interact with several neurotransmitter receptors, including dopamine, GABA, and glutamate.

In addition to its role in neurotransmission, the STMN3 protein is also involved in the regulation of neuronal excitability and has been shown to play a role in the modulation of action potential (AP) in neurons.

The potential drug target status of the STMN3 protein is due to several factors. Firstly, the protein is expressed in high levels in the CNS and has been shown to be involved in the transmission of signals between neurons. Secondly, the protein has been shown to interact with several neurotransmitter receptors, making it a potential target for drugs that can modulate neurotransmission.

The identification of the STMN3 protein as a potential drug target has led to a growing body of research aimed at understanding its role in the CNS and the potential benefits and risks of targeting it with drugs. One of the main goals of this research is to develop drugs that can modulate neurotransmission and improve the treatment outcomes for neurological disorders.

In conclusion, the STMN3 protein is a promising drug target in the CNS due to its involvement in neurotransmission and its interaction with neurotransmitter receptors. Further research is needed to fully understand its role in the CNS and to develop effective treatments for neurological disorders.

Protein Name: Stathmin 3

Functions: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3

The "STMN3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about STMN3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

STMN4 | STMND1 | STMP1 | STN1 | STOM | STOML1 | STOML2 | STOML3 | STON1 | STON1-GTF2A1L | STON2 | Store-operating calcium channel channels | STOX1 | STOX2 | STPG1 | STPG2 | STPG3 | STPG3-AS1 | STPG4 | STRA6 | STRA6LP | STRA8 | STRADA | STRADB | STRAP | STRBP | STRC | STRCP1 | STRIP1 | STRIP2 | STRIT1 | STRN | STRN3 | STRN4 | STS | STT3A | STT3A-AS1 | STT3B | STUB1 | STUM | STX10 | STX11 | STX12 | STX16 | STX16-NPEPL1 | STX17 | STX17-DT | STX18 | STX18-AS1 | STX18-IT1 | STX19 | STX1A | STX1B | STX2 | STX3 | STX4 | STX5 | STX5-DT | STX6 | STX7 | STX8 | STXBP1 | STXBP2 | STXBP3 | STXBP4 | STXBP5 | STXBP5-AS1 | STXBP5L | STXBP6 | STYK1 | STYX | STYXL1 | STYXL2 | SUB1 | SUB1P1 | Succinate Dehydrogenase Complex | Succinate-CoA ligase (ADP-forming) | SUCLA2 | SUCLG1 | SUCLG2 | SUCLG2-DT | SUCLG2P2 | SUCNR1 | SUCO | SUDS3 | SUFU | SUGCT | SUGP1 | SUGP2 | SUGT1 | SUGT1P1 | SUGT1P2 | SUGT1P3 | SUGT1P4-STRA6LP-CCDC180 | SULF1 | SULF2 | Sulfotransferase | SULT1A1 | SULT1A2 | SULT1A3