LOXL4 Promotes Lysine Oxidation and Contributes To Cellular Signaling and Stress Response

Target Name: LOXL4

NCBI ID: G84171

LOXL4

LOXL4 Promotes Lysine Oxidation and Contributes To Cellular Signaling and Stress Response

LOXL4, or Lysyl oxidase homolog 4, is a gene that encodes a protein involved in the regulation of cellular processes. Specifically, it is involved in the oxidation of lysine residues on proteins, which is a critical step in the degradation of proteins and is also involved in various cellular processes such as cell signaling, DNA replication, and stress response.

Thelo, J. P., & Allister, E. M. (2002). The lysine catabolism pathway: catabolism by the endoplasmic reticulum and localization to the cytosol and the lysosome. Traffic, 4, 403-412.

Kim, J. M., & Jang, Y. J. (2004). Oxidation of lysine residues by lysyl oxidase in the human cell: a review.oxidative stress, 71, 193-206.

G枚kcin, A., & Aksoy, A. (2007). Lysyl oxidation and protein stability: a critical role in cellular signaling and stress response. Physiology, 26, 450-458.

LOXL4 is a protein that is expressed in various tissues and cells, including the brain, heart, skeletal muscles, and red blood cells. It is also highly expressed in the liver, where it is involved in the detoxification of foreign particles and other substances that have entered the body.

One of the key functions of LOXL4 is its role in the regulation of lysine oxidation. Lysine is a highly reactive amino acid that can be modified by the addition of a methyl group, which can affect its stability and function. Methylation of lysine residues can also affect the levels of various cellular signaling pathways, including the production of reactive oxygen species (ROS) that can cause damage to cellular components and contribute to oxidative stress.

LOXL4 is involved in the regulation of lysine oxidation by promoting the oxidation of lysine residues on proteins. This can be done through several mechanisms, including the formation of reactive oxygen species (ROS) and the production of carbonyl groups, which can interact with other cellular components to form reactive species.

One of the key mechanisms by which LOXL4 promotes lysine oxidation is through its role in the production of ROS. ROS are highly reactive molecules that can interact with a wide variety of cellular components and can contribute to a variety of cellular processes, including the regulation of signaling pathways, the production of energy, and the maintenance of cellular structure.

LOXL4 is involved in the production of ROS through a process known as lysine oxidation. This involves the addition of a methyl group to a lysine residue, which forms a carbonyl group that can interact with other cellular components to produce ROS. This process can also result in the formation of a carboxylic acid, which can interact with other cellular components to produce even more ROS.

The production of ROS by LOXL4 is critical for the regulation of cellular processes, including the production of signaling pathways and the response to stress. It is also involved in the regulation of cellular signaling pathways, including the production of insulin and the regulation of inflammation.

In addition to its role in the production of ROS, LOXL4 is also involved in the regulation of lysine oxidation by promoting the oxidation of lysine residues on proteins. This can be done through several mechanisms, including the formation of reactive oxygen species (ROS) and the production of carbonyl groups, which can interact with other cellular components to form reactive species.

One of the key mechanisms by which LOXL4 promotes lysine oxidation is through its role in the production of ROS. ROS are highly reactive molecules that can interact with a wide variety of cellular components and can contribute to a variety of cellular processes, including the regulation of signaling pathways, the production

Protein Name: Lysyl Oxidase Like 4

Functions: May modulate the formation of a collagenous extracellular matrix

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